Senior Scientist, Immunology

Fremont, California
Jun 11, 2018
Required Education
Position Type
Full time

Position Description: 

Asterias Biotherapeutics is seeking a talented and dynamic scientist for a Senior Scientist position in the Regenerative Medicine and Immune-oncology Product Development team. This individual will be directly responsible for executing experiments and leading ongoing efforts in the discovery and development of novel stem cell therapies for advancement into the clinic. The position will actively support projects both in early and late stage development across multidisciplinary teams.

Summary of Essential Job Functions:

  • Drive discovery and translational efforts to support projects aimed at optimizing the differentiation of human pluripotent stem cells into desired cell types
  • Manage and identify key external collaborations that would enhance decisions on projects and/or yield new target indications
  • Lead efforts for development of in vitro cell-based assays to characterize the phenotype and potency of candidate cell therapies
  • Contribute to the hands-on development and performance of immune-monitoring assays for patients receiving candidate cell therapies
  • Apply knowledge and know-how internally on project teams as well as represent  the company externally
  • Lead identification and testing of novel scientific /technical opportunities
  • Design and execute experimental plans, provide interpretation, troubleshoot and suggest next steps
  • Maintain laboratory notebooks in a professional, and accurate manner
  • Interact and collaborate with members of all other departments at Asterias, including Analytical Technologies, Process Development, and Clinical Operations
  • Prepare study reports and presentations for group meetings, conferences, publications and regulatory filings

Minimum Requirements

  • Ph.D. degree with 5 or more years post-graduate experience related to the field of immune-oncology and stem cell biology
  • Preference will be given to candidates with a strong background in T cell immunology and dendritic cell biology
  • Proven record of applicable immunology or immune-oncology relevant publications
  • Proficient cell culture techniques of human cell lines, pluripotent stem cells, and primary cells
  • Hands-on experience with isolating, culturing, and expanding antigen-specific lymphocytes from human whole blood
  • Immunological techniques (Multi-color flow cytometry, ELISpot, and ELISA), Cell-based immunoassays (MLR, CTL assays)
  • Basic molecular biology techniques (DNA/RNA preparation, qPCR, cloning)
  • Requires up to 5-10% international travel
  • Computer skills in Excel, PowerPoint, word processing, and data presentation
  • Excellent organizational, communication, and written skills