GEM Ops Technical Manager
At Bristol-Myers Squibb, we're creating innovative medicines for patients who are fighting serious diseases. We're also nurturing our own team with inspiring work and challenging career options. No matter our role, each of us makes a contribution. And that makes all the difference.
Position: Operations/Technical Manager II for Genetically Engineered Models (GEMs)
Location: Redwood City, CA
We are seeking an Operations/Technical Manager II specializing in supervision and colony management of the GEM program to join the Veterinary Sciences team. As such you will experience a culture that believes in making the animal care and use program a model for the industry. We are focused on providing employees with career development and activities across our entire drug development process.
Bristol-Myers Squibb is the industry leader in immuno-oncology with life-saving medicines and a rich clinical portfolio of diverse modalities including monoclonal antibody, antibody drug conjugate, fusion protein, and combination regimes.
• Manages the daily operations of the barrier breeding facility specializing in the production of GEMs and other colony production breeding.
• Manages routine to moderately complex breeding colonies.
• Actively monitors quality of activities, operations, and projects, and makes day-to-day decisions related to production breeding and facility operations.
• Works closely with VS staff and other groups to optimize breeding programs. Recommends and implements colony management improvements.
• Collaborates with other groups and departments to address requests.
• Oversees selection of founders for breeding, works with technicians to ensure breeders are set up and monitored effectively, drives and coordinates collection of tissues for genetic analysis.
• Assists in the oversight of daily activities and development of staff and programs.
• Supervises and provides leadership and motivation to VS staff performing the work and ensures they have adequate training and mentoring to support the efforts.
• Leads the reviews and updates VS Standard Operating Procedures (SOPs) according to the assigned review schedule.
• Trains staff on new or revised SOPs.
• Trains technical staff in the daily activities of GEM and colony production system.
• Reviews staff work assignments and ensures quality performance of assigned tasks.
• Works hand in hand with the Transgenic Modeling and other groups to develop an understanding of their needs and offer solutions related to the projects being managed.
• Responsible for upholding regulatory and welfare standards as they pertain to laboratory animal care, husbandry, facilities, and the overall animal macro environment.
• Sets standards and provides guidance on daily operations, animal room preparation, environmental parameters, and relevant reports and takes corrective action as necessary.
• Updates and maintains information systems related to project and study data.
• Manages and develops assigned staff consistent with Company strategy and to achieve departmental objectives.
• Leads supervisory team in developing cross functional capabilities and building team effectiveness.
• Recommends, develops, and delivers training programs for VS employees and research staff on proper techniques required for compliance with research protocols.
• Supervises the maintenance, use, disposition, and inventory of equipment for animal care or laboratory activities.
• Provides assistance with major project/program activities in the department which may involve multi-site interactions.
• Provides weekend and holiday supervisory and management coverage on a rotational basis.
Competencies - Knowledge, Skills, Abilities:
• The individual is required to have knowledge of GEM colony production breeding, experimental methodology, facility operations, and knowledge of regulations and guidelines that rodent breeding operations.
• Must have mastery of all VS SOPs and a good understanding of related departmental procedures (EH&S, Facilities, etc.) and proficiency in integrating this knowledge with strategic objectives.
• Understanding of regulatory compliance (i.e. USDA regulations and Animal Welfare Act) and accrediting guidelines (AAALAC and The Guide for the Care and Use of Laboratory Animals) for facility operations.
• Must have outstanding team building skills and demonstrated leadership and managerial abilities.
Experience - Responsibility and minimum number of years:
• Must have a history of consistent, sustained high-level performance, and typically attained with 15 years relevant experience in a GEM colony production breeding programs.
• Must have an excellent understanding of research methodologies and requirements used at this site.
• Must have an excellent understanding of research animal facility operation, to include animal welfare practices, husbandry procedures, animal health and veterinary care, enrichment program, and applicable regulations/accreditations (USDA, AAALAC, OLAW, and site/departmental SOPs).
• Must have excellent verbal and written skills
• Must be able to train and supervise technical staff in GEM rodent production systems.
• Bachelors of Science (BS) in life sciences with a minimum of 15 years of relevant experience is required.
• Masters of Science (MS) in Molecular Biology or Laboratory Animal Science and/or a Masters of Business Administration (MBA) is required.
• Individual must have AALAS certification at the Laboratory Animal Technologist (LATG) level.
• AALAS certification at the Certified Manager of Animal Resources (CMAR) is preferred.
• PhD in Molecular Biology or equivalent degree in life sciences is preferred.