Research Associate 1, Analytical Development
About CytomX Therapeutics:
CytomX Therapeutics is a clinical-stage biopharmaceutical company with a deep and differentiated oncology pipeline of investigational Probody™ therapeutics. Probody therapeutics are designed to exploit unique conditions of the tumor microenvironment to more effectively localize antibody binding and activity while limiting activity in healthy tissues. The Company’s pipeline includes proprietary cancer immunotherapies against clinically-validated targets, such as PD-L1, and first-in-class Probody drug conjugates against highly attractive targets, such as CD166 and CD71, which are considered to be inaccessible to conventional antibody drug conjugates due to their presence on healthy tissue. In addition to its wholly owned programs, CytomX has strategic collaborations with AbbVie, Amgen, Bristol-Myers Squibb Company, MD Anderson Cancer Center and ImmunoGen, Inc. For more information, visit www.cytomx.com or follow us on Twitter.
Location: South San Francisco, California
This position requires the ability of the candidate to support protein analytics and characterization needs for CytomX Therapeutics’ discovery and development programs. The position will provide analytical support to upstream and downstream process development and formulation in the analysis of in-process and final product samples. The position entails the execution and development of HPLC and gel based analytical methods for in-depth protein characterization. Working knowledge of CE-SDS and icIEF is a plus. The individual will be required to diligently document experimental work in notebooks, and may be required to write (or may contribute to writing) SOPs and reports.
Bachelor of Science (BS) degree in Biochemistry, Analytical Chemistry or related discipline with 1-2 years’ experience in the biotechnology industry or a Master of Science (MS) degree in Biochemistry, Analytical Chemistry or related discipline with 0-2 years of industry experience.
Experience with running HPLC and gel based analytical methods for characterization of proteins/biopharmaceuticals is essential. In-depth knowledge in the use of analytical instrumentation, especially Agilent and Thermo (Dionex) HPLCs, as well as maintaining and troubleshooting analytical equipment is required. Ability to independently perform experiments and multi-task with minimal supervision and prior experience in developing and qualifying analytical methods for biopharmaceuticals is highly desirable. Prior experience supporting process development or formulation is a plus. Good verbal and written communication skills are essential. The candidate must be able to work collaboratively and efficiently in a team environment. He/She must be well organized, have a strong work ethic and be diligent in data documentation.
CytomX is an equal opportunity employer. Employment decisions are based on merit and business needs. CytomX will not discriminate against any job applicant because of race, color, national origin, ancestry, gender, sexual orientation, age, religion, creed, physical or mental disability, gender identity, medical condition, pregnancy, marital status, veteran status, or any other characteristic protected by federal, state or local law.