Associate/Sr. Associate/Principal Associate, Process Development - Downstream

Location
San Diego
Posted
Jun 01, 2018
Required Education
Bachelors Degree
Position Type
Full time

PaxVax, Inc. is seeking an Associate/Sr. Associate/Principal Associate for Process Development & Production.  The successful candidate will work with a team focused on process development for vaccine development from preclinical through Phase III and commercialization. The main responsibilities will include the design, execution, and documentation of experiments to develop/optimize downstream processes (chromatography purification, diafiltration/ultrafiltration) for clinical supply production and to scale up these processes to enable transfer of robust processes to the commercial stage. The incumbent will assist the scientific staff in carrying out research assignments involving a variety of laboratory methods, equipment and procedures. The successful candidate will be required to work in a fast-paced team oriented environment and be able to learn new skills quickly. This is an incredible opportunity to join a growing clinical stage pharmaceutical company with a bright future.

Responsibilities:

  • Good understanding of bio-chemical and physical properties of therapeutic biomacromolecules including but not limited to proteins and virus particles
  • Viral or virus like particle purification by chromatography and ultrafiltration
  • Understanding of the drug product manufacturing process and scale-up considerations
  • Generate SOPs, batch records and technical reports as required

Qualification Requirements:

  • Bachelor’s degree in Biology, Molecular Biology or related discipline with minimum of 2-5 years’ relevant industry experience or an MS degree plus the knowledge and skills acquired through 1 years’ relevant industry experience
  • Team player and collaborator, ability to listen and communicate clear and timely manner
  • Self-motivated and detail oriented is a must
  • Good aseptic techniques required
  • Anion Exchange Purification experience is required
  • Diafiltration/Ultrafiltration experience is preferred
  • Column packing, cleaning and evaluation experience is preferred
  • cGMP experience is preferred
  • Process development / manufacturing experience is preferred
  • Skilled with use of word processing, spreadsheets, graphical and presentation software applications
  • Excellent written and verbal communication skills