Research Associate - Human Anti-Tumor Immune Cell Lab

Tarrytown, New York, US
May 13, 2018
Required Education
Masters Degree/MBA
Position Type
Full time
Position Summary

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Position Summary:

We are looking for a Research Associate to join our Immuno-Oncology Group. The successful candidate will work on a team that develops and executes functional T cell assays using clinical specimens. The assays include both direct ex vivo analysis as well as in vitro immune cell culture. The candidate should be experienced with culturing primary human T cells and antigen presenting cells, as well as basic functional immune assays such as ELISPOT assays and T cell stimulation assays.
The position also requires mastery of multi-color (12+) flow cytometry. Other preferred technical skills include experience with basic molecular biology and protein biochemistry techniques, including nucleic acid isolation, PCR, and Western blotting.


Job Responsibilities
• Independently isolate PBMC from human peripheral blood.
• Derive human dendritic cells from human PBMC.
• Isolate tumor infiltrating immune cells from human tumor resections for phenotypic and functional analyses.
• Perform T cell functional assays including ELISPOT.
• Independently perform antibody and multimer staining for multiparameter flow cytometry; independent operation of flow cytometer.
• Collaborate with internal research and clinical teams to develop and perform human T cell functional assays.

This position requires a minimum of an MS Degree in immunology or related discipline and 3 years of experience in T cell immunology and hands-on technical experience in primary immune cell culture.. Additional requirements include:

• Excellent organizational skills.
• Strong written and oral communication skills
• Experience working in cross-functional teams

Required skills: Multiparameter flow cytometry, primary human T cell culture, immune cell functional assays, basic molecular biology and protein biochemistry experience, ELISA, ELISPOT.

Preferred experience: Tumor immunology, tumor dissociation.

Level will be commensurate with experience

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Requisition Number: 13017BR