Associate Translational Clinical Scientist, Clinical II

Lake County, Illinois, USA
May 08, 2018
Required Education
Bachelors Degree
Position Type
Full time
Associate Translational Clinical Scientist, Clinical II

AbbVie Oncology Development is seeking a highly motivated and skilled translational scientist with a proven track record of accomplishments in the cancer field. Strong communication and teamwork skills are essential as the candidate is expected to operate in a fast-paced and multi-disciplinary environment and to interact with diverse groups of experts from within or outside of their scientific discipline. The candidate must be able to prioritize and manage multiple research activities. Background in hematologic malignancies, programmed cell death/apoptosis, and/or classical oncogenic signaling pathways strongly preferred.

  Key Responsibilities Include:
  • Define and implement translational biology research strategies for multiple oncology therapeutic programs.
  • Independently conceive and execute experimental strategies to identify/validate rational drug combinations and elucidate biological mechanisms of action.
  • Prioritize and manage multiple collaborative research activities and maintain a broad range of knowledge and technical expertise in cancer biology.
  • Work closely with internal and external collaborators to generate high quality preclinical- translational data sets that inform clinical development strategies and decision making.
  • May initiate new areas of investigation that are scientifically meaningful, reliable, and can be incorporated directly into a research or development program.
  • Act as primary author of publications, presentations, regulatory documents and/or primary inventor of patents.
  • Prepare and present summaries of preclinical data to key stakeholders across multiple functional areas, including Drug Discovery, Development, Biomarkers, Regulatory, Commercial, etc.
  • Contribute to clinical protocols, regulatory documents and key decisions impacting development plans and project timelines.
  • Assess preclinical research proposals from external researchers for scientific content; prioritize proposals with greatest potential for enhancing internal development programs.
  • Apply experience to analyze clinical study data, including statistical data and blinded/un-blinded PK, safety and efficacy to ensure scientific integrity.
  • Integrate clinical trial data across multiple studies and identify issues impacting projects; communicate findings to internal/external peers and function/therapeutic area management.
  • Perform literature/competitive intelligence searches to recognize/resolve scientific and technical problems associated with preclinical and/or clinical studies.
  • Independently complete tasks and assignments from Therapeutic Area MD or Scientific Staff within timeline and with minimal supervision.
  • Bachelors/Master's degree, in cancer-related field with 8+ years of relevant experience in pharmaceutical industry. Ph.D. in Cell/Molecular Biology, Biochemistry, Genetics/Genomics, Pharmacology, Oncology or related field with 3+ years of experience preferred.
  • Candidate must demonstrate a strong background in cancer biology with knowledge of and experience in hematologic malignancies (for example, ALL, AML, CLL, CML, MDS, MPNs, multiple myeloma, non-Hodgkin lymphomas, etc.), cell signaling pathways, therapeutic approaches (small molecules and biologics) and the regulation of programmed cell death/apoptosis.
  • Translational research experience preferred - for example, demonstrated ability to apply preclinical research findings to clinical settings.
  • Working understanding of clinical study principles (design, objectives, inclusion/exclusion criteria, response assessments, statistics, etc.)
  • Must possess strong oral and written communication skills and demonstrate an ability to navigate complex interactions with internal and external collaborators.
  • Impactful research experience as demonstrated by track record of publications, patents and/or scientific accomplishments is essential, as is the ability to engage internal and external scientific leaders in collaborative research.
  • Ability to produce scientific data sets of the highest quality by paying attention to detail.
  • Ability to appropriately and effectively use resources to complete tasks and meet required timelines.
Equal Opportunity Employer Minorities/Women/Veterans/Disabled