Senior Principal Research Scientist, Medicinal Chemistry

Lake County, Illinois, USA
May 08, 2018
Required Education
Bachelors Degree
Position Type
Full time

The candidate will be responsible for driving medicinal chemistry of assigned projects and ensuring the deliver high quality tools, leads and candidate molecules within competitive time-frames. The candidate will participate in planning and implementing the short-term strategy and long-term vision of the Centralized Medicinal Chemistry group within the Discovery Chemistry and Technology organization. He/she will be responsible for developing medicinal chemistry strategies and ensuring efficient execution of tactics to meet project goals. The candidate will provide scientific oversight and accept accountability of all medicinal chemistry activities in assigned projects. Responsibilities will include managing a medicinal chemistry team of multiple MS/PhD-level scientists within ongoing hit to tool and lead optimization projects. The candidate will develop the capabilities of the staff through mentoring and by promoting a culture that embraces open scientific debate and agile, accountable decision-making. He/she will ensure the team maintains the highest laboratory safety standards. The candidate will effectively augment SAR by coordinating medicinal and synthetic organic chemistry outsourcing activities and collaborations within assigned projects. The candidate must be able to anticipate challenges and creatively apply knowledge of the latest concepts and technology platforms to solve problems. The successful candidate must demonstrate strategic thinking and have excellent communication skills. He/she will effectively communicate to internal and external partner pharmacology groups and senior management through oral presentations and written reports. The candidate must establish strong, productive relationships with key partners and diverse groups across R&D disciplines through clear, transparent communication of medicinal chemistry strategies and progress. He/she will build a strong network and ensure visibility in the medicinal and synthetic organic chemistry field by participation in scientific meetings and by publishing high quality science.


  • BS, MS, or PhD/PostDoc in synthetic organic/medicinal chemistry.

  • 18+ (BS), 16+ (MS), or 10+ (Ph.D) years medicinal chemistry and drug discovery industrial experience.

  • Experience with all phases of drug discovery from hit identification to delivery of development candidates using state-of-the-art platform technologies.

  • Proven ability to innovate and a track record of significant scientific contributions with publications in peer-reviewed journals and protection of intellectual property through patents.

  • Experience effectively managing, supervising and leading other professionals.

  • Exceptional communication skills; ability to develop, implement and clearly communicate chemistry/project strategies to team, management and collaborators.

  • Strong interpersonal and influencing skills and comfort working in a rapidly changing environment.

  • Ability to lead the delivery of candidate transitions through LO and clinical candidate selection.

  • Ability to work across disease/therapeutic areas and diverse teams.

Key Leadership Competencies:

  • Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
  • Learns fast, grasps the "essence" and can change course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Equal Opportunity Employer Minorities/Women/Veterans/Disabled