Scientist, Protein Engineering & Characterization

Worcester, Massachusetts, USA
May 08, 2018
Required Education
Bachelors Degree
Position Type
Full time
We are seeking a highly motivated and creative scientist with a background in protein engineering, expression, purification and analytical characterization to join the AbbVie Global Biologics Discovery organization. This individual will work in drug discovery cross-functional teams both internally and externally to design, produce, characterize and test recombinant proteins for different therapeutic areas including metabolic diseases, oncology, immunology and aging. Responsibilities:
  • Execute hands on scientific research involving engineering, production and screening of recombinant tool and therapeutic proteins, including antigens, antibodies, fusion proteins and multi-specific biologics.
  • Apply various protein analytical methods to characterize and test recombinant proteins in relevant biochemical and cellular experiments.
  • Work collaboratively with matrixed project teams and members of the Global Biologics Group to drive innovation and deliver novel therapies for patients.
  • Develop productive collaborations and communication with other groups across therapeutic areas.
  • Timely documentation of experiments and activities in electronic archive systems.
  • Engage colleagues in cross-disciplinary scientific discussion, present scientific data to internal and external audiences and publish research in peer-reviewed journals.
Position will be hired based on the level of experience.


  • BS, or MS degree in biochemistry or related discipline with 5-7+ (BS),or 2-5+ (MS) years of relevant experience in academic or biotech/pharmaceutical industry setting.
  • Extensive expertise in recombinant protein production, proficiency in analytical techniques for protein characterization (such as mass spectrometry, chromatography and others).
  • Hands-on experience in molecular cloning, and designing/producing novel bi-specific proteins in mammalian and bacterial cells, is highly desired.
  • Proficiency in biochemical assay development including MSD, ForteBio, and receptor ligand interaction assays is desirable.
  • Familiarity with molecular modeling is a plus.
  • Experience in biochemistry and cellular biology of metalloproteinases is a plus.
  • Strong communication and organization skills, especially the ability to work across multiple scientific disciplines and functions.
  • Managerial experience for one or more direct reports is highly desirable.
  • Strong record of performance and scientific accomplishments as demonstrated by impactful contributions to the scientific community, pipeline contributions, peer reviewed publications and patent applications.
Equal Opportunity Employer Minorities/Women/Veterans/Disabled