Laboratory Scientist - MHC Tetramer Production

MBL Bion/International
Des Plaines, Illinois
May 01, 2018
Required Education
Bachelors Degree
Position Type
Full time

Purpose of Work:

Responsible for performing procedures specific to the production of MHC tetramers and to ensure manufactured products supplied to the customer meet the highest quality standards.

Essential Job Functions and Duties:

  • Perform laboratory processes involved in manufacturing and/or QC of products and the preparation of reagents/media.
  • Utilization of Good Manufacturing Practices (GMP) and Good Laboratory Practices (GLP).
  • Protein purification techniques utilizing the AKTA FPLC and UNICORN Software. 
  • Protein analysis techniques utilizing HPLC, spectrophotometry, and SDS-PAGE.
  • Cellular analysis by cell staining and Flow Cytometry
  • Conduct testing for shelf-life studies on product retention samples.
  • Perform incoming inspection of Raw Materials as required.
  • Complete all required paperwork and records in a clear and succinct fashion as required by the department manager.
  • Clean-up work area and dispose of biohazard or other waste materials appropriately.
  • Ability to recognize anomalies in the production process, make adjustments, and inform management regarding areas of improvement.
  • Operate and maintain department related equipment.
  • Order and stock supplies as needed and conduct monthly inventory of supplies.
  • Familiar with the Quality Management System and quality policies.
  • Familiar with applicable regulatory requirements (GMP)
  • Working Knowledge of safety program procedures.

Other Job Duties:

Performs other duties as required

Minimum Qualifications of the Position:


Bachelor’s degree in life sciences, biology, chemistry, biochemistry or closely related field. 


Must have 2 years of experience in protein purification and analysis. Prefer prior MHC tetramer preparation experience and/or experience in immunology and immune-oncology. Experience in Flow Cytometry is desirable.

Knowledge, Skills, Abilities:

  • Good communication skills, both written and verbal
  • Ability to speak and write English and communicate scientific principles in English
  • Ability to follow instructions, both written and verbal
  • Strong organizational skills
  • Strong troubleshooting skills
  • Good manual dexterity
  • Ability to perform laboratory procedures without supervision
  • Ability to operate laboratory equipment
  • Good team player
  • Ability to multi-task effectively
  • Ability to follow routine manufacturing processes without mistake or alterations.
  • Must deliver on time results that are clearly written and can be articulated.

Physical Requirements of the Position:

Type of Work Environment:

 Manufacturing Laboratory