Sr. Research Associate, Upstream Process Sciences

94043, Mountain View
Apr 30, 2018
Sr. RA, Upstream Process
Required Education
Bachelors Degree
Position Type
Full time

Sr. Research Associate, Upstream Process Sciences

IGM Biosciences is a privately held, biotechnology company focused on the discovery and development of innovative therapeutic antibodies for the treatment of cancer, autoimmune disorders and infectious diseases.  Since 2011, we have pioneered a new field of antibody development by creating novel IgM and IgA antibodies.  Our proprietary platform of high avidity, natural and engineered human antibodies utilizes novel mechanisms of action that specifically target cell types involved in disease pathways. We are building a strong pipeline of biologics for oncology, infectious disease and immunology disease drug candidates.

We are seeking a collaborative and driven Sr. Research Associate to work alongside our Process Sciences Group.  This position supports the development of novel antibody products by helping to create upstream processes producing these therapeutic antibodies. The Senior Research Associate is expected to maintain and expand cells, support the upstream PD lab and to set up and execute antibody production runs at scale up to 25 liters or larger if needed. 


Essential Duties and Responsibilities:

  • Maintains and passages CHO expression cell lines.
  • Transfects plasmids into expression cells for transient production
  • Selects and expands expression cell lines for both stable and transient production
  • Maintains upstream development lab
  • Determines expression titer by ELISA and other techniques.
  • Documents results in laboratory notebooks.
  • Shares data with management and team members.
  • Searches the literature to identify alternative methodologies and solve scientific problems, establish, and qualify assays.
  • Prepares technical reports, summaries, and detailed protocols
  • Learns new techniques as the job requires.


Desired Education, Skills and Experience:


  • BS/BA or higher degree in a biology related discipline
  • 3-5 years of relevant experience
  • Experience working with mammalian cell culture and bioreactor/wave systems
  • Work in BSL-2 conditions
  • Knowledge of basic computer programs routinely used in a lab such as MS Word, Powerpoint, Excel, GraphPad, etc.
  • Ability to quickly learn and master new instrument software and programs.
  • Excellent organization, interpersonal, and communication skills.
  • Being a team player and respectful of others is a must.
  • Experience in maintaining thorough lab records, and adhering to health and safety regulations
  • Ability to thrive in a fast-paced, small start-up environment



The job description outlined above reflects general details as necessary to describe the primary functions of this job, the level of knowledge and skill typically required, but should not be construed as an all-inclusive listing of work requirements. Individuals may be asked to perform duties other than those mentioned above in order to cover absences or relief in the appropriate department to equalize peak work periods or otherwise balance the workload.

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.