Scientist, Chemistry

Location
Jupiter, Florida
Posted
Apr 25, 2018
Required Education
Doctorate/PHD/MD
Position Type
Full time

Scientist, Chemistry

Summary

Perform research in the laboratory as a synthetic and medicinal chemist applying the latest knowledge and techniques in the field.  Advance the assigned program and contribute to the identification of a lead or development candidate.  

Essential Functions

  • Design and execute syntheses of complex organic molecules on a milligram to multi-gram scale
  • Use advanced laboratory techniques to purify mixtures of compounds
  • Use state of the art techniques to characterize intermediates and final compounds
  • Rationally design a series of target molecules for a pharmacological target of interest
  • Use medicinal chemistry tools and techniques to plan and design synthetic targets
  • Communicate results to co-workers and management in both oral and written manner and assist in the preparation of patent applications

Qualifications                 

  • Ph.D. in synthetic organic chemistry strongly preferred; a combination of relevant education and applicable job experience may be considered
  • 1-2 years of post-graduate experience working in the biotechnology or pharmaceutical industry or a related position as a laboratory scientist
  • Highly proficient in advanced synthetic, purification and spectroscopic techniques utilized in the preparation and characterization of complex organic molecules
  • Demonstrated ability to design synthetic targets and successfully execute their syntheses
  • Several first author or co-author publications in peer-reviewed journals demonstrating research accomplishments is preferred
  • Familiarity with Structure-Based Drug Design
  • Firm understanding of modern Medicinal Chemistry concepts and the ability to use them in the design of target molecules or to improve the properties of existing compounds
  • Ability to work effectively in teams and collaborate with other scientists including microbiologists, structural biologists, pharmacologists and toxicologists
  • Self-starter with a strong work ethic and ability to work independently and show flexibility when needed
  • Effective oral and written English communication skills
  • Familiarity with standard laboratory instrumentation, computers, and office and laboratory software

About Expansion Therapeutics

Expansion Therapeutics is a drug discovery and development company pursuing the vast potential of small molecule medicines for RNA-mediated diseases. We are initially focused on expansion repeat disorders, a set of ~30 genetic diseases for which there are no satisfactory therapies. Our lead disease focus, myotonic dystrophy type 1 (DM1), is the most frequent cause of adult onset muscular dystrophy. Expansion has assembled an initial focused pipeline of compositions targeting repeats that drive a number of expansion repeat disorders. For more information or to apply for this position, please visit our website htttps://www.expansionrx.com