Senior Scientist I/II, Immuno−Oncology Genomics
Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products — Imbruvica, Venclexta, and Empliciti — and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. This position is based in AbbVie's Redwood City location.
POSITION DESCRIPTION:Conceive and execute novel next generation sequencing research or development assays that achieves projects goals. Generate new scientific proposals and lead those efforts. Investigate, identify, develop, and optimize new methods and techniques. Act as a lead scientist in next generation sequencing field and critically evaluate relevant scientific and regulatory advances and integrate this knowledge into research and development programs.
Key Responsibilities include:
- Organize, schedule, and monitor sequencing projects
- Identify and validate technologies that allow efficient and innovative next generation sequencing study using preclinical samples.
- Conceive and develop novel next generation sequencing assay schemes including nucleic acid extraction with residue samples and library preparation with minimum input materials.
- Demonstrate the ability to resolve next generation sequencing project hurdles and assumptions by effectively utilizing available information and technical expertise.
- Publish next generation sequencing related research work in peer-reviewed journals and present work at scientific conferences.
- Seize opportunities to pursue project relevant leads that are in line with the team's strategy.
- Maintain a high level of productivity in the lab.
- Work closely with bioinformatics team to define analysis strategies for next generation sequencing project planning as well as data optimization.
- Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials where applicable.
Senior Scientist I: Bachelor's Degree or equivalent education and typically 10 years of experience, Master's Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary.
Senior Scientist II: Bachelor's Degree or equivalent education and typically 12 years of experience, Master's Degree or equivalent education and typically 10 years of experience, PhD and typically 4 years of experience.
- Possess thorough theoretical and practical understanding of own scientific discipline.
- Effective writer and communicator of research or other regulatory materials.
- Experience developing high-throughput assays based on next generation, as evidenced by peer-reviewed publications or published patents.
- Experience in single-cell genomics, functional genomics or immunology significant plus.
- Experience in quality control analysis of sequencing data a significant plus.
Equal Opportunity Employer Minorities/Women/Veterans/Disabled