Senior Scientist II/III - Ligand Binding Assays

Worcester, Massachusetts, USA
Apr 13, 2018
Required Education
Bachelors Degree
Position Type
Full time
The DMPK Department at AbbVie Bioresearch Center in Worcester, MA supports Discovery teams focused on finding novel therapeutic agents for the treatment of immunological diseases.

In addition the Ligand Binding Assay group provides biomarker support for Immunology and has global responsibilities in providing non-GLP PK and ADA methods and sample analysis for biologics projects across all therapeutic areas at AbbVie.

The Senior Scientist will:

  • Be responsible for biomarker and bioanalytical (PK and ADA) method development to support studies in various experimental animal species and within clinical settings.
  • Represent DMPK-BA on teams to provide guidance on bioanalytical issues, ensure alignment and manage timelines.
  • Work with team of dedicated scientists developing new assays for bi-specifics and antibody-drug conjugates
  • Evaluate and recommend new assay platforms to accelerate bioanalysis of projects from early discovery to development.

The candidate is expected to lead evaluation of suitable methodologies for assessing biomarkers and protein therapeutics in various biological matrices.

Candidate should have experience working under Pharmaceutical Guidelines.

*Level will be based on education & years of experience*

PhD in life science-related fields with 0-3+ years of method development experience in the pharmaceutical industry required PhD in life science-related fields with 4+ years of method development experience in the pharmaceutical industry PREFERRED Experience in developing Ligand Binding Assays (LBAs) to assess biomarkers, PK and immunogenicity under the recommended industry guidelines Experience in supervising junior scientists in developing and troubleshooting bioanalytical methods and managing priorities Excellent oral & written communication skills Proven track record in scientific excellence Experience in working in a multidisciplinary team setting Excellent interpersonal skills and collaborative spirit to work with colleagues across sites and across disciplines Ability to process complex information quickly and deliver concise messages to the target audiences Hands-on experience in multiple LBA platforms is a plus Strong immunology background is an advantageEqual Opportunity Employer Minorities/Women/Veterans/Disabled