Bristol-Myers Squibb Company

Principal Clinical Biomarker Scientist Associate Director - Oncology

Princeton, NJ, US
Apr 12, 2018
Required Education
Position Type
Full time
Bristol-Myers Squibb is actively conducting translational medicine research to further our understanding of cancer biology and to identify which patient populations may be more likely to derive benefit from Immuno-Oncology (I-O). Bristol-Myers Squibb has long believed the future of cancer research is dependent on investments in science and partnerships. Collaboration is integrated into our organizational framework across translational medicine and R&D.

The Clinical Biomarker Scientist is responsible for developing and executing on translational strategies for the Oncology pipeline. This scientist works on various projects across all stages of drug development and will act as a key interface with the Translational Medicine group.

The successful candidate will be responsible for integrating translational research and clinical development, developing a biomarker strategy in alignment with clinical development objectives, leading efforts for data generation, interpretation and communication to the development teams. The candidate will also be responsible for understanding the external research environment, partnering with discovery biology and other functions both internally and with external partners to coordinate the execution of deliverables.

• Effectively engages with development teams and technical/scientific experts to define, revise and progress translational/biomarker plans.

• Helps in the delivery of high quality biomarker strategies for target engagement, pharmacodynamic endpoints and patient selection, under the supervision of other biomarkers (where appropriate).

• Provides insight into novel ways to incorporate biomarkers into clinical designs to enable early understanding of emerging drug profiles.

• Effectively interfaces with the Translational Medicine group to obtain appropriate resources to deliver on biomarker goals.

• Evaluates and interprets analytical/scientific data and drives the integration of that data into knowledge across programs.

• Offers innovation to senior leadership team to contribute to Clinical Biomarker Department's evolution to future state.

• Has broad therapeutic area and/or core technology views and awareness to help develop strategies to implement these tools appropriately across the portfolio.

• As appropriate, provides biomarker expertise to progress validated biomarkers into development of pharmacodiagnostic tools.

This position is based in Lawrenceville, New Jersey


• MD or PhD, or equivalent advanced biology degree

• Experienced scientist with 7+ years' experience in the drug development process.

• Deep understanding of the role of translational research/medicine and clinical biomarkers in drug development

• Comfortable working in a fast-paced environment where speed is paramount

• Willing to work as a topic expert, outside of a traditional functional environment, in a team unified around serving the assets

• Ability to recognize, articulate, and accept calculated risks to make informed decisions

• Willingness and ability to effectively cooperate and partner with external providers, senior leaders, and others within BMS

• Demonstrated experience in the appropriate application of various scientific technologies into translational research strategies

• Working knowledge of all functional areas of drug development, including, biology, toxicology, clinical development, diagnostic development, etc.

Demonstrated scientific acumen and mechanistic understanding of disease biology