Research Scientist Computational Genomics

Boston, Massachusetts
Apr 09, 2018
Science/R&D, Genomics
Required Education
Position Type
Full time

We are seeking a highly motivated data scientist with expertise in transcriptomic or proteomic analysis (or a related computational biology skill) to join Vertex’s research site in Boston, MA. This position will be part of a growing global Computational Genomics function, and will provide key support for the new Chemical Biology function in our continuing efforts to find novel, innovative treatments for serious human diseases. You will report directly to the Sr. Director of the Computational Genomics group. A key task will be to integrate internal and public data from chemical and genetic screens, proteomics experiments, and transcriptome profiling to discover new targets or pathways, help understand mechanism of action, and propose new experimental directions in close collaboration with project teams, screening groups, and other data scientists. Strong collaboration and communication skills are therefore essential. 

Minimum Qualifications

PhD degree in computational biology, bioinformatics, human genomics, or a related field in the biological data sciences, ideally with relevant post-doc experience (<4 years).

  • A proven track record in the analysis, visualization and interpretation of large “omics” data sets.
  • Solid understanding of statistics and expertise in R and Python.
  • Expert knowledge of human genome annotation and biological pathway resources, and familiarity with systems biology concepts and best practices of software development.
  • Familiarity with high-performance computing and databases.
  • Excellent communication skills and ability to work both independently and collaboratively across our global research organization.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases. We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases. 

Founded in 1989 in Cambridge, Mass., Vertex today has research and development sites and offices around the world. For several consecutive years, Science magazine has named Vertex one of its Top Employers in the life sciences. For additional information and the latest updates from the Company, please visit 

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at