Dynavax Technologies

Research Associate II/III

Berkeley, California
Mar 23, 2018
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
 This position will be responsible for providing analytical chemistry and formulation support for small molecule, oligonucleotide and protein-based drug candidates to  advance Dynavax’s immuno-oncology research programs in the field of Toll Receptor agonism.




  • ·         Conduct laboratory-based analytical chemistry and formulation research activities with small molecule, oligonucleotide and/or protein-based drug candidates, including; compound formulation, sample management, analytical method development / optimization, and bioconjugation chemistry.


    ·         Contribute to the design and execution of in vitro and in vivo PK/DM experiments.


    ·         Execute experimental protocols and collect / record results, must be able to effectively troubleshoot experiment procedures.


    ·         Analyze experimental data, prepare and submit technical reports, and present results at project team and departmental meetings.


    ·         Coordinate day-to-day laboratory activities to ensure reagents are available and maintenance of equipment.


    ·         Document all scientific work in lab notebooks, follow established Dynavax standard operating procedures on data documentation and notebooks, and adhere to Dynavax Quality Systems standards.


    ·         Support the organization in maintaining a work environment focused on quality and that fosters learning, open communication, collaboration, integration, and team work.


    ·         Other duties as assigned.



·         BS or MS in life science, either in chemistry, biochemistry and/or other related discipline.


·         Required experience will vary depending on level:  RA II level with BS and 3+ years relevant experience; RA III level with BS and 5+ years, or an MS with 2+ years’ of relevant experience.


·         Relevant laboratory experience includes:

-   small molecule / oligonucleotide / protein compound formulation and management.

-   purification / analysis of small molecules, oligonucleotides, and / or proteins by high or low pressure LC methods (RP, SEC, HIC, etc.).

-   other analytical methods, including SDS-PAGE, UV spectroscopy, DLS, zeta-potential, endotoxin determination, etc.

-   familiarity with bioconjugation chemistries / methodology.

-   experience with harvesting tissues from laboratory mice and processing for bioanalysis.


·         Proficiency with Word, Excel, Powerpoint, Prism, and ChemDraw software.


·         Must be capable of working independently, have careful attention to experimental details, and possess excellent record-keeping and strong organizational skills. 


·         Excellent written and verbal communication skills.


Additional knowledge and skills desired, but not required:

·         Mass spectroscopy and its application to the field of biotechnology.


·         Familiarity with fundamental concepts in immuno-oncology.