Associate Scientist – ImPACT Process (PD)

PACT Pharma
Hayward, California
Mar 21, 2018
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time

PACT Pharma is an exciting new company in the San Francisco Bay Area.  PACT is developing personalized adoptive T cell therapies for the eradication of solid tumors. The identification of neo-epitopes that serve as private mutations for each patient’s cancer creates a unique opportunity to engineer autologous T cells that target and kill tumors expressing these neo-antigens.  PACT utilizes technology licensed from the laboratories of Drs. Heath and Baltimore (Caltech) to identify T cells that recognize the neo-epitope.  The unique T-cell receptor (TCR) sequences obtained from these neoepitope-reactive cells are then engineered into T cells from the patient’s own blood to produce PACT’s therapeutic product: a tsunami of fresh, active T cells that, following infusion into the patient, recognize and attack each patient’s cancer cells.

We are currently recruiting for several positions across the spectrum of roles at the company. We are located in the San Francisco Bay Area, in the heart of the world’s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including aggressive participation in the growth of the company in the form of stock option grants.  PACT Pharma is an ambitious cutting-edge undertaking - we fully anticipate our company to become the world’s leader in personalized adoptive T cell therapies for cancer and therefore key to the future of cancer treatment. We are currently located in Hayward.

Associate Scientist – Impact Process

She/he will be responsible for the design and execution of critical path experiments for the discovery of neoEpitope and corresponding TCR, to be to be used for the manufacture adoptive cell therapeutics (ACT). These experiments will focus on flow cytometric analysis of patient samples and engineered T cells, and may also include operation of microfluidic devices, RT-PCR, and NGS analysis of single T cells. The ideal candidate should enjoy operating in an exceptionally dynamic and cooperative environment.

Minimum Qualifications:

  • The ideal candidate should hold a Bachelor’s degree with 7+ years’ experience, hold a Master’s degree with 3+ years’ experience, or hold a PhD in a relevant field, with career focus in immunology or immuno-oncology.
  • Proficiency at cell-based bioassays, single cell technologies, FACS and RT-PCR
  • The candidate should be highly goal-driven and have demonstrated the ability to focus on time-sensitive objectives.
  • Experience with fluid handling robots will be a plus
  • Experience with microfluidics or immuno-oncology will be a plus
  • Familiarity with T cell biology
  • She/he must have excellent organizational skills and should be able to communicate clearly and concisely, both verbally and in the form of written reports

Interested candidates should send a cover letter, C.V. and Research Summary.