Associate Scientist I/II/Scientist I, Pharmaceutical Development, Formulation

Redwood City, California, USA
Mar 15, 2018
Required Education
Bachelors Degree
Position Type
Full time
Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products — Imbruvica, Venclexta, and Empliciti — and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer. AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments.

AbbVie Biotherapeutics (ABR) is AbbVie's Center of Innovation in Oncology Research and Development, located in Redwood City, CA. ABR research and development efforts are focused on three key areas:

1. Targeted antibody therapies that inhibit cancer cell growth, proliferation and survival

2. Antibody drug conjugates (ADCs) that allow for potent toxins to be directed to cancerous cells while sparing healthy tissues

3. Immuno-Oncology (I-O), which activates the immune system to recognize and eliminate cancer cells

ABR employs approximately 160 individuals in the San Francisco Bay Area. Its size and entrepreneurial work force allows for effective cross-functional collaboration, agility and rapid decision making.

We have an exciting opportunity available for an Associate Scientist I/ Associate Scientist II/Scientist I at ABR in the Pharmaceutical Development Group. This position will support development of liquid and lyophilized dosage forms for preclinical and clinical protein therapeutics in development at ABR.

Key responsibilities include:

Conduct stability studies to enable selection of formulation composition and container closure for liquid and lyophilized dosage forms for antibody therapeutics Conduct drug product process development studies as well as product end-use studies to guide dose solution administration Provide data analysis and documentation for technical reports, presentations and regulatory filings QUALIFICATIONS

Associate Scientist I: Bachelor's Degree, or equivalent education
Associate Scientist II: Bachelor's Degree, or equivalent education, with typically 3 or more years' experience or Master's Degree or equivalent education
Scientist I: Bachelor's Degree or equivalent education with typically 5 years of experience, or Master's Degree or equivalent education with typically two years of experience.

  • Hands-on experience with analytical techniques used for protein characterization and stability testing
  • Prior protein formulation development experience highly preferred
  • Excellent communication and written skills required
Equal Opportunity Employer Minorities/Women/Veterans/Disabled