Analytical Lab Manager

Employer
Grifols
Location
Emeryville, CA
Posted
Mar 13, 2018
Ref
61231
Required Education
Bachelors Degree
Position Type
Full time

Primary responsibilities for role:

  • Manages a team of Associates performing laboratory-based studies in either Fermentation (microbial and mammalian fermentation, scale up, fed batch, culture analysis), Purification (recombinant protein purification, IEC, GFC, RP-HPLC, HIC and other process improvements) or Analytical Methods (HPLC, SEC, DLS, Mass Spectroscopy, SDS PAGE, Silver Stain, Western Blot, ELISA, for in-process and release testing) to support process characterization, process improvement or investigations into process-related deviations.
  • Provides leadership, motivation and career development of laboratory staff
  • Acts as the key point of contact for study owners for related studies and be the group representative in team meetings
  • Manages the laboratory budget and preparing the annual budget forecast and capital equipment requests
  • Prepares CARs and all other required forms for laboratory equipment purchases and facilities modifications/improvements
  • Identifies staff that perform each study according to required number of fermentations, purifications or analytical tests and complexity of the study
  • Maintains a monthly experimental schedule for the Laboratory running whenever possible at a capacity of >80%
  • Review and approves Technical Protocols, Method development and Qualification reports
  • Ensures timely review of all data supporting technical studies.
  • Ensures laboratory equipment and instrumentation upkeep which include troubleshooting, PM/calibration/qualification as needed
  • Ensures staff are on-boarded and compliant with required trainings
  • Communicates frequently with senior colleagues on project timing, progress and issues promptly.
  • Provides weekly and monthly progress reports to Director of TD.
  • Communicates with personnel from other Departments such as Facilities, Engineering Metrology/Calibration, Supply Chain Management, and Technical Services, to ensure laboratories are operational at least 48 weeks per year

 

Additional Responsibilities:

  • All equipment and the facility is maintained in a usable state at least 48 weeks per year
  • All Associates have appropriate career development plans and are actively pursuing the agreed activities
  • Hiring appropriately qualified personnel to fulfill teams functions and responsibilities
  • Studies are completed on agreed time lines.
  • Laboratory operates at a capacity of >80% whenever possible
  • Functional group operates within expected budget target amount

 

Knowledge, Skills, and Abilities:

  • Capable of effective use of Microsoft Word, Excel and Powerpoint
  • Strong working knowledge of DOE approaches for experimental design
  • Extensive working knowledge developing and qualifying analytical assays 
  • Very strong ability to plan and coordinate complex studies involving multiple departments
  • Excellent written and verbal communication skills

 

Education:

Ph.D. in Protein Biochemistry, Molecular Biology, or a related life sciences discipline.

 

Experience:

  • 10+ years of experience with a Ph.D. in Analytical Development, Process Development environment in the biotechnology or diagnostics industry
  • Strong understanding of microbial and Mammalian derived recombinant protein processes and Analytical characterization of recombinant proteins and monoclonal antibodies is highly desirable.  
  • At least 5 years previous experience managing a team of Associate Scientists
  • Previous experience developing budget forecasts would be advantageous
  • Experience working with design of experiments approaches and Process Analytical tools.