Formulation Scientist (NCI)

21701, Frederick
Mar 12, 2018
Required Education
Position Type
Full time


The Nanotechnology Characterization Lab (NCL) serves as a national resource and knowledge base for all cancer researchers to facilitate the regulatory review of nanotechnologies intended for cancer therapies and diagnostics.  By providing the critical infrastructure and preclinical characterization services to nanomaterial providers, the NCL accelerates the transition of basic nanoscale particles and devices into clinical applications.


Formulation Scientist

The Nanotechnology Characterization Lab (NCL) provides nanotechnology formulation and characterization services for universities, the pharmaceutical industry and other government programs (


  • Will provide support for chemical synthesis, nanoformulation and scale-up to NCL's formulation customers
  • Will also assist in physicochemical characterization and development of new analytical methods for evaluating nanomedicines
  • Therefore, filling this position is mission critical.



  • Possession of a Doctoral degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in pharmaceutical science, analytical chemistry, medicinal chemistry, biomedical engineering or related discipline. (Additional qualifying experience may be substituted for the required education). Foreign degrees must be evaluated for U.S. equivalency.
  • In addition to educational requirements, candidates should have had two (2) or more years of competent, innovative research experience beyond doctoral training in a related field of specialty.  Proficiency in developing test or production methods or protocols in an applied area; demonstrated ability to manage a production operation or a segment of a specialized service area.  An individual at this level normally has made contributions by independently producing research work of such originality, soundness, and value as a significant contributor in the field by authoring and co-authoring publications in peer-reviewed scientific journals and by presenting papers before national professional societies.
  • Must be able to obtain and maintain a security clearance.


  • Familiarity with drug development and the pharmaceutical industry; understanding of CMC for IND/IDE applications; some knowledge of drug metabolism-pharmacokinetics (DMPK)

Expected Competencies:

  • Experience should include demonstrated synthetic and analytical skills with respect to the formulation of small and complex macromolecules using nanotechnology-based drug delivery platforms
  • strong background in lipid and/or polymer chemistry, as well as in-depth understanding of nanomaterials physicochemical properties and their characterization is required
  • Experience with physicochemical characterization of nanoparticles using state-of-the-art instrumentation and methods such as SEC, MALLS/DLS, AFFFF, MS, TEM, NMR, AFM, HPLC, SANS and SAXS. 
  • Experience preparing data summaries and scientific presentations in the form of lectures, posters and manuscripts.
  • Ability to perform complex assignments independently as well as work effectively as part of an interdisciplinary team.