Research Technician, In vivo immunopharmacology

Research Triangle Park, NC 27709
To commensurate with experience
Feb 27, 2018
Required Education
Bachelors Degree
Position Type
Full time

Research Technician, In vivo immunopharmacology

Location: Research Triangle Park, NC 27709

Position type: Full Time

About TCRCure Biopharma Corp.:

Founded in May 2017, TCRCure Biopharma is a clinical stage biopharmaceutical company focused on the discovery and development of engineered autologous T cell products for cancer immunotherapy. Specifically, we identify novel chimeric antigen receptor (CAR) targets, modify CAR designs, and deploy CARs and T cell receptors (TCRs) to redirect patients’ T cells against tumors.

Job Description:

The Research Technician, In vivo immunopharmacology will work closely with project scientists to design and execute immune-oncology related mouse studies and evaluate novel cancer therapies. Must be able to work in a team environment and contribute to ongoing studies. May be asked to assist in some technical support duties. Must be able to understand and follow Institutional Animal Care and Use Committee (IACUC) guidelines and policies. Individual must understand and follow local, state, and federal regulations and guidelines.


  • Build and maintain syngeneic, xenograft, and orthotopic mouse cancer models
  • Perform mouse in vivo animal procedures, including dosing by various routes (e.g. intravenous and intraperitoneal)
  • Perform efficacy and tolerability testing in mouse cancer models
  • Animal health monitoring
  • Mouse necropsy and tissue collection
  • Cell culture
  • Data recording, data analysis, reporting, and interpretation
  • Contribute to overall vivarium organization and IACUC protocol

Education and Experience Requirements:

- B.S. in Biological Sciences or a related scientific discipline; M.S. preferred

- Experience with mice including handling, tumor modeling, dosing, and efficacy studies

- Proficiency with standard statistical analysis software (e.g. Microsoft Office, Graph Pad Prism)

- This position requires a highly self-motivated individual, with outstanding organizational skills and the ability to effectively present results and conclusions to co-workers, collaborators and managers. Ability to work well under pressure and drive personal and team objectives

To Apply:

TCRCure Biopharma provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, disability, genetic information, marital status, amnesty, or status as a covered veteran in accordance with applicable federal, state and local laws. TCRCure Biopharma complies with applicable state and local laws governing non-discrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including, but not limited to, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.

If you are interested in applying for this opportunity, please submit your resume or CV and cover letter to