Dr. Larry Corey’s laboratory at the University of Washington (UW) and Fred Hutchinson Cancer Research Center is recruiting for a motivated Research Scientist with experience in genetically engineering T cells. The Research Scientist will collaborate with the Principal Investigator to expand work in adoptive transfer studies of lymphocytes for infectious diseases by conceiving and developing projects and plans for new approaches to immunologic elimination of infectious agents. This job is devoted to constructing and assessing the in vitro and eventually in vivo evaluation of genetically engineered cells for HIV-1 and HPV-related tumors. Knowledge of CAR T-cell biology, xenograft models, in vitro cytolytic assays, gene protection of T cells, and engineering novel homing molecules into cells are just some of the projects involved. The lab is expert at in situ diagnostics and in situ detection of T cells.
The Department of Laboratory Medicine at UW serves as a regional resource for clinical laboratory services required for patient care, research and educational programs in laboratory medicine. UW is proud to be one of the nation’s premier educational and research institutions. Our people are the most important asset in our pursuit of achieving excellence in education, research, and community service. Our staff not only enjoys outstanding benefits and professional growth opportunities, but also an environment noted for diversity, community involvement, intellectual excitement and natural beauty. The Fred Hutchinson Cancer Research Center, where Dr. Corey’s laboratory is located, is a world-renowned cancer center located in the South Lake Union neighborhood of Seattle.
- Knows lentiviral transfection systems and cultivation of T cells
- Independently designs diagnostic testing using flow cytometry, phagocytosis assays, lentivirus transfection and other clinical and research assays, and determines assay performance and diagnostic utility
- Analyzes experimental data and determines what modifications and follow-up experiments are necessary to generate relevant data
- Contributes data and analyses for grant submissions; presents data at laboratory meetings; writes manuscripts with Principal Investigator for peer-reviewed journals and prepares abstracts and posters for conference proceedings
- Develops appropriate and creative solutions and chooses best alternatives; takes action in a timely manner
- Effectively informs staff of policies, procedures, expectations, and objectives; solicits feedback from employees on an ongoing basis
- Fosters team effort and cooperation among staff members, both intra- and interdepartmentally
- Trains and helps manage employees
- Performs other duties as required
This position provides opportunities to work in a fast-paced, challenging, diverse and rewarding environment. As an employee, you will enjoy generous benefits and work/life programs. For detailed information on Benefits for this position, click here.
- Doctorate in Virology, Immunology or relevant related field and three to five years in related area or equivalent combination of education/experience.
- Experience in T-cell immunology and/or B-cell immunology with flow cytometry, phagocytosis assays and lentivirus transfection experience
- Evidence of strong writing skills, meticulous record keeping and superb organization, ability to bring projects to completion, and effective collaborator
- Experience with multidimensional flow cytometry, single cell genomics
For further details and to apply please visit our employment site at www.uw.edu/jobs and apply directly to req# 152586.