Eli Lilly and Company

Research Scientist-Pancreatic Islet Biology

Location
Indianapolis, Indiana
Posted
Feb 06, 2018
Ref
36579BR
Required Education
Doctorate/PHD/MD
Position Type
Full time

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Responsibilities

Do you have expertise in islet cell biology? Are you a passionate and dedicated scientist with diabetes complication research experience? The Diabetes and Complications Therapeutic Area (DCTA) at Lilly is looking for a Research Scientist – Islet Biology, who can play a key role in developing novel therapeutics that halt or revert progression of diabetes. You will establish a state-of-the art research laboratory focused on pancreatic beta cell biology, with emphasis on islet cell development, differentiation and function. You should have strong knowledge and technical skills in the field of Diabetes, Metabolism and Islet Biology with particular focus on the molecular mechanisms regulating islet cell development, differentiation and function. You will have the chance to define and progress projects from target identification to proof-of-concept testing in man, working collaboratively with scientists in the DCTA and with internal and external partners. Are you inspired by the science and the desire to make a difference? Consider joining Lilly to make an impact in the lives of our patients.

 Potential opportunities in this role include:

  • Discover, validate and advance novel molecular targets to address beta cell dysfunction in Diabetes.
  • Design, conduct and lead studies in preclinical animal models, isolated pancreatic islets and cultured cells, aligning resources to meet short- and long-term goals.
  • Supervision of the islet morphometry platform and/or significant strategic and project leadership.
  • Provide preclinical biology leadership on cross-functional project teams by partnering in a team-driven approach to expeditiously tackle challenges and advance projects.
  • Advance molecular understanding of the mechanisms of the beta cell failure through research and collaborations with team colleagues and academic investigators.
  • Maintain scientific expertise and presence in the external scientific community through publication, collaborations, and presentations in the areas of diabetes and metabolic disease.

Basic Qualifications       

  • Ph.D. with at least 1 year of relevant post-doc or work experience
  • In-depth expertise in diabetes pathophysiology and pancreatic beta cell biology highly preferred.

Additional Skills/Preferences   

  • Proficiency in islet isolation and culture, analysis of beta cell differentiation, proliferation and death both ex vivo and in vitro, routine molecular biology and biochemical techniques, and in vivo animal models of diabetes.
  • Experience with imaging highly desirable.
  • Proven track record of scientific accomplishments as evidenced by high impact publications.
  • Ability to work collaboratively with diverse groups while advancing project and strategic goals.
  • Excellent oral and written communication skills.
  • Previous supervisory experience and expertise in drug discovery a plus.

Additional Information

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.