Research Associate (NCI)

Location
Frederick, Maryland
Posted
Jan 31, 2018
Ref
648770
Discipline
Science/R&D, Research
Hotbed
BioCapital
Required Education
Bachelors Degree
Position Type
Full time

PROGRAM DESCRIPTION

The Molecular Characterization Laboratory (MoCha) is part of Leidos Biomedical Research’s Clinical Research Directorate (CRD) at the Frederick National Laboratory for Cancer Research. The MoCha Laboratory is responsible for providing high-level research in support of the NCI-Cancer Diagnostics Program (CDP) within the Division of Cancer Treatment and Diagnosis (DCTD). MoCha is charged with the development and application of genomic assays for use in medical research and diagnostics for DCTD-sponsored national extramural clinical trials.

KEY ROLES/RESPONSIBILITIES

The Research Associate will be the technical lead in nucleic acid extraction, nucleic acid quality control, specimen accessioning and tracking to facilitate cutting edge genomic research in support of DCTD projects e.g. Patient Derived Xenograft Models (PDM) project, genomic characterization of patient samples enrolled in clinical trials.

  • Perform nucleic acid extractions manually or using automated platforms
  • Perform quality and quantitation assays on extracted nucleic acids in high throughput assay platforms
  • Accession and track biospecimens from multiple projects
  • Perform appropriate dilutions of the extracted nucleic acids for downstream genomic assays using automated platforms
  • Recommend and optimize new nucleic QC assay platforms
  • Recommend and optimize biospecimen tracking processes
  • Develop new assays and apply the methods/assays utilizing sound scientific judgement
  • Take lead role in above-mentioned activities
  • Develop and maintain SOPs for above-mentioned research activities
  • Perform formal reporting of research data, including presentations and/or scientific publications
  • Make detailed observations, analyze data and interpret results
  • Investigate, create and develop new methods and technologies for project advancement
  • May participate in scientific conferences and contribute to scientific journals
  • Maintain knowledge of the most recent literature and scientific presentations relevant to projects
  • Maintain essential laboratory supplies and monitors equipment for optimum performance

This position will be located in Frederick, Maryland.
Qualifications:

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

This is a dual level requisition. It may be filled at either a Research Associate I or Research Associate II level.

Basic Qualifications for a Research Associate I:

  • Possession of a Bachelor's degree in a relevant field from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) (Additional qualifying experience may be substituted for the required education); Foreign degrees must be evaluated for U.S. equivalency
  • In addition to the education requirements, a minimum of 2 years of relevant experience

Basic Qualifications for a Research Associate II:

  • Possession of a Bachelor's degree in a relevant field from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) (Additional qualifying experience may be substituted for the required education); Foreign degrees must be evaluated for U.S. equivalency
  • In addition to the education requirements, a minimum of 5 years of relevant experience

Both the Research Associate I and Research Associate II positions require:

  • Strong technical skills in molecular assays and/or nucleic acid extraction and understanding of quality control metrics of nucleic acids
  • Ability to independently evaluate the suitability and quality control of research or production assays or tests
  • Ability to develop and follow SOPs and analyze and report data
  • Ability to track information in a large cohort of samples and monitor progress of multiple projects
  • Adequate computer skills to document, organize, and present experimental data
  • Must be able to obtain and maintain a security clearance

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:

  • Experience in automated nucleic acid extraction platforms
  • Experience in workflow automation platforms (sample dilution robotic platforms)
  • Familiarity with clinical oncology studies and other protocol-driven clinical research

Expected Competencies:

  • Understanding in molecular biology techniques, oncology and clinical research
  • Excellent communication skills (written and oral)
  • Ability to work effectively in a matrix and team‐oriented environment
  • Strong critical thinking and problem solving skills
  • Strong organizational and multitasking skills