Position Role: The successful candidate would be expected to lead as well as conduct, hands-on, translational research and pre-clinical studies pertaining to our endothelial cell, stem cell and gene therapy programs. Taking the helm for the development and completion of INDs is expected, utilizing internal and external (expert consultant) resources in a time-efficient and cost-effective manner. This is a role for a person who enjoys leading (and wants to grow as a leader), thinks through the strategy and study designs, and gets the studies done.
Our client is currently focused on utilizing its proprietary E-CEL technology as a direct therapeutic product for improving Hematopoietic Stem Cell Transplants (HSCTs), as well as offering a novel therapy for the regeneration of damaged tissues resulting from both acute and chronic disease. As such, the applicant must have
- At least 4 years’ post-graduate hands-on laboratory experience (post-doc or industry experience) covering both in vitro and in vivo work in the fields of vascular biology and hematopoiesis.
- More specifically, experience in personally conducting translational studies that are designed for providing the essential data sets necessary for pre-IND and IND applications is required.
- Demonstration of high-level thinking and effective communication skills, through both writing and oral presentation, would be expected.
- The successful candidate would exude thoughtfulness, ‘can do’ attitude, penchant for creative problem solving and the passion to overcome challenges and obstacles to realize science to clinical reality.
- The person in this role would be comfortable being a leader of his/her area and a productive member of a cross-functional team.
- This person is not bothered by fast-paced evolution and change, nor fearful of taking on the unknown and unfamiliar.
- (1) Ph.D. in cell biology, molecular biology, biochemistry, microbiology or related field; and (2) Postdoctoral fellowship or equivalent industry experience in stem cell gene therapy research and cell engineering.
- While not a requirement, solid familiarity in cell therapy, gene-editing, and monogenic hematologic diseases would be a great plus.
- More specifically, prior knowledge in assessing viral and non-viral transduction/transfection efficiencies, as well as experience in integration proficiency, vector design and viral copy number of the delivered gene product(s) would be highly desirable.
- Applicant needs to have a strong publication record and solid recommendations verifying his/her previous work.