Research Associate/Senior Research Associate, Cardio- and Metabolic Diseases
NGM Biopharmaceuticals, Inc. is a private, maturing biotech start-up dedicated to discovering the next generation medicines to treat grave diseases. Our experienced scientific team has joined forces with an impressive group of industry professionals, Nobel Laureates, and other distinguished researchers to form a company where innovation and cutting edge science will provide the foundation for a robust drug discovery engine. In 2015, we established a broad collaboration with Merck that will provide us with the resources and flexibility to pursue our ambitious research and development goals. This partnership is a strong validation for NGM as a biologics discovery engine that will generate transformational medicines for unmet medical needs.
We are currently looking for a creative, highly motivated and experienced individual to join our target discovery and drug development efforts. The successful candidate will play an integral role as a key team member in a group focused on the in vivo characterization and evaluation of novel drug targets. He/She must properly use laboratory and animal enrichment procedures to meet IACUC protocol and established guidelines.
•Perform pharmacology and MOA studies in rodent models of disease focusing on the characterization of novel drug targets and drug candidates across a number of disease indications
•Develop and establish new animal models in cardiovascular and metabolism diseases
•Collaborate closely with other team members, present results in cross-functional team meetings and deliver presentations to both small and large groups
•Bachelor or Master Degree in a scientific discipline with at least 6 years of work experience in pharmacology or animal science
•Superior animal (rats and mice) handling skills, including in in vivo study conduct; husbandry, dosing by multiple routes (IV, PO, IP), observation recording, blood, tissue collection and necropsy
•Experience with design and execution of rodent pharmacology studies
•Sustained productivity evidenced by contribution to IND filings and/or patent or literature publications
•Knowledge of rodent models of obesity/diabetes/oncology/inflammation
•Experience in small animal survival surgeries is preferred
•Strong sense of urgency and commitment to excellence
•Strong desire to "make things happen"
•Thrives in a collaborative environment
•Passion for the drug discovery