Research Associate III (Ligand-Binding Assay/ELISA/PK)
We are seeking a highly motivated, Research Associate to join the Bioanalytical/Bioassay Development Department at Nektar Therapeutics. The successful candidate will be responsible for developing and performing Ligand Binding Assays (e.g. ELISAs, ECLAs) for pharmacokinetic (PK), toxicokinetic (TK) and anti-drug antibodies (ADAs) assessments to advance research, pre-clinical, and clinical stage programs. The successful candidate will also be responsible for performing routine tasks as directed to maintain the laboratory.
Analyze clinical samples in compliance with GCP regulations and Nektar’s SOPs. Manage clinical sample inventory including receipt, login/logout and disposal. With guidance, develop complex assays for measuring the PK/TK of Nektar’s PEGylated-protein, drug candidates. Compile data and analyze results in terms of quality/validity. Document all activities in the electronic notebook. Perform routine equipment maintenance, calibrations, and verifications as per SOP. Collaborate with other bioanalytical team members to complete tasks and meet departmental goals. Collaborate with members of other departments to complete tasks when required. Prepare study reports and SOP revisions.
A minimum of a Bachelor’s degree in biology, biochemistry, or other related scientific discipline with 5+ years of work experience. Equivalent experience may be accepted. In depth technical knowledge to understand the caveats of Ligand Binding Assays and to recognize issues during development and sample analysis. Experience performing and developing Ligand Binding Assays for PK/TK and is required. Experience working in a GCP/GLP environment is desirable. Knowledge of ADA assay development and validation is desirable.
Ability to work on multiple task/projects at the same time. Ability to work in a fast-paced, goal-oriented environment. Effective time-management skills.
Self-motivated to carry out both new and routine tasks. Detailed oriented and able to follow instructions. Must be willing to work as part of a team and demonstrate good interpersonal skills.
Proficient working with Microsoft Word, Excel, and PowerPoint. Past experience with electronic notebook systems a plus.