Technology Development Research Associate

Location
Berkeley, California
Posted
Jan 12, 2018
Discipline
Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time

Caribou Biosciences, Inc. is a leading company in CRISPR genome engineering located in Berkeley, CA. Caribou's tools and technologies provide transformative capabilities to therapeutic development, agricultural biotechnology, industrial biotechnology, and basic and applied biological research. The five-year-old company has developed a best-in-class CRISPR genome engineering technology platform and has a leading intellectual property position.

We are seeking an experienced Research Associate (RA) to join our Technology Development group. The ideal candidate will interact closely with Scientists and other RAs to support a variety of efforts aimed at developing and optimizing genome engineering tools and procedures.  Overall, the candidate should have a strong background in mammalian cell culture, molecular biology, and next-generation sequencing (NGS).

Responsibilities will include:

Mammalian tissue culture

  • Culture of primary mammalian cells and immortalized cell lines
  • Mammalian cell transfection

Molecular biology

  • DNA construct design (e.g., using standard sequence manipulation software), PCR, molecular cloning, plasmid purification, interpretation of Sanger sequencing results 

Next-generation sequencing (NGS) and analysis

  • In collaboration with core facilities, prepare and analyze Illumina sequencing libraries 

General

  • Coordinate experiments with other Scientists and RAs across functional groups, compile data and present results, and stay current on relevant primary literature

Candidate must possess:

  • B.Sc. or equivalent in Cell Biology, Bioengineering, Biochemistry, Immunology, Genetics, or a related field
  • Minimum of 3 years of experience working in a biotech, pharmaceutical, or academic laboratory setting  
  • Significant experience culturing and transfecting a range of primary mammalian cell types
  • Experience with preparation and/or analysis of Illumina sequencing libraries
  • Significant experience with conventional molecular biology techniques such as PCR, cloning, Sanger sequencing analysis, and plasmid purification
  • Strong desire to work on early-stage projects in a fast-paced, rapidly evolving field
  • Strong organizational, time management, communication, and interpersonal skills

Pluses:

  • M.Sc. or equivalent in Cell Biology, Bioengineering, Biochemistry, Immunology, Genetics, or a related field
  • Experience working with mammalian genome editing technologies and procedures

Caribou Biosciences, Inc. is a dynamic start-up company, and the successful candidate must have the ability and desire to work in a fast-paced environment.  For more information, please visit www.cariboubio.com.  Caribou is on Twitter @CaribouBio.

Caribou offers a comprehensive compensation package, as well as generous paid time off in addition to Company-observed holidays.  The Company provides medical, dental, and vision insurance, along with a 401(k) retirement savings plan which includes matching employer contributions. Caribou promotes a culture in which employees are respected and rewarded for hard work, innovation, personal initiative, and teamwork.  

Caribou is an equal opportunity employer and does not unlawfully discriminate on the basis of race, color, religion, citizenship, political activity or affiliation, marital status, age, national origin, ancestry, physical or mental disability, medical condition (as defined under California law), veteran status, sexual orientation, gender identity, gender expression, sex or gender (which includes pregnancy, childbirth, breastfeeding, or related medical conditions), taking or requesting statutorily protected leave, or any other basis protected by law. In addition, Caribou prohibits the harassment of any individual on any of the bases listed above or any other characteristics protected under federal, state, or local laws.

Direct applicants only. No agencies please.