Scientist / Technical Leader, Screening – NITD

Location
Emeryville, California
Posted
Oct 20, 2017
Ref
223073BR
Required Education
Bachelors Degree
Position Type
Full time

The Novartis Institute for Tropical Diseases (NITD), relocated to Emeryville, California, is dedicated to fighting parasitic infectious diseases of high medical need in a dynamic working environment. NITD is an independent Institute within the Novartis Institutes for Biomedical Research (NIBR), and as such has full access to NIBR know-how and resources including the chemists of the Global Discovery Chemistry group and the Infectious Diseases drug discovery teams (antiviral and antibacterial) co-located in Emeryville. NITD is renowned for applying cutting-edge technologies to the discovery of high quality clinical candidates for the treatment of neglected diseases. The Institute has a highly collaborative culture and has close links with academic centers of excellence and a broad range of non-governmental and philanthropic organizations around the globe (Wellcome Trust, Bill and Melinda Gates Foundation, Medicines for Malaria Venture and Drugs for Neglected Diseases Initiative).

About the position:
We are seeking a biologist with extensive expertise in screening technologies and automated robotic platforms. The successful candidate will be responsible for design and implementation of biochemical and cellular screens that support the discovery and characterization of novel anti-parasitic drugs.

Specifically the candidate will:
• Design, develop, automate, and execute biochemical and cell-based assays for high-throughput screening
• Manage an automated screening platform, including site-wide scheduling and prioritization across multiple disease areas
• Act as ambassador to biology groups for translation of assays to screening platform
• Work productively with engineering team to maintain system operation and build future capabilities
• Troubleshoot assays and instrumentation
• Ensure integrity, quality, and timely delivery of data
• Interpret complex results and provide input to multidisciplinary project teams supporting discovery of drug candidates

Minimum requirements

• Bachelor’s or Master’s degree or equivalent in relevant discipline, with 5+ years of experience
• Experience with small molecule assay development, lead discovery, and lead optimization in a drug discovery setting
• Demonstrated expertise of automating assays on screening platforms
• Demonstrated ability to critically evaluate and achieve assay robustness, reproducibility, and data quality
• Comfortable with biosafety level 2 (BSL2) research
• Keen interest in anti-infective drug discovery and infectious disease
• Excellent written and verbal communication skills
• Innovative mindset and collaborative spirit
• Positive attitude and “can-do” mentality