Transforming Skin Cells into Cartilage, Osaka City University Graduate School of Medicine Study
Published: Jan 11, 2011
EurekAlert! -- In this paper, Noriyuki Tsumaki and his team at the Osaka University Graduate School of Medicine, used fibroblasts isolated from adult mouse skin, and expressed proteins used to induce pluripotency along with a factor that promotes a chondrocyte fate. The resulting cells resembled chondrocytes and produced cartilage when injected into mice. This may be an important step toward a therapy that will allow the repair of cartilage injury using a patient's own skin cells.