Substance in Tangerines Fights Obesity and Protects Against Heart Disease, University of Western Ontario Research Suggests
Published: May 26, 2011
Flavonoids are compounds found in plants, often as pigments, that are highly anti-oxidative and anti-inflammatory. Nobiletin, which is found in citrus fruits, occurs in its highest concentration in tangerines. The Canadian scientists also found that nobiletin protected the lab mice from atherosclerosis, arterial plaque build-up that can lead to heart attack or stroke.
The research leader, Murray Huff, a vascular biologist at the university, had previously found a flavonoid in grapefruits, naringenin, that offered lab mice protection against obesity. Huff said, however, that nobiletin offers 10 times the level of protection against obesity that naringenin does.
Results of the Canadian study, published in the medical journal Diabetes, open the door for studies on nobiletin's effects on human test subjects.