Stowers Scientists Successfully Expand Bone Marrow-Derived Stem Cells in Culture, Stowers Institute for Medical Research and University of California, San Francisco (UCSF) Study
Published: Sep 07, 2011
All stem cells regardless of their source share the remarkable capability to replenish themselves by undergoing self-renewal. Yet, so far, efforts to grow and expand scarce hematopoietic (or blood-forming) stem cells in culture for therapeutic applications have been met with limited success. Now, researchers at the Stowers Institute for Medical Research teased apart the molecular mechanisms enabling stem cell renewal in hematopoietic stem cells isolated from mice and successfully applied their insight to expand cultured hematopoietic stem cells a hundredfold.