See-Through "MitoFish" Opens a New Window on Brain Diseases, Technische Universitat Munchen Study
Published: Dec 06, 2012
Scientists have demonstrated a new way to investigate mechanisms at work in Alzheimer's and other neurodegenerative diseases, which also could prove useful in the search for effective drugs. For new insights, they turned to the zebrafish, which is transparent in the early stages of its life. The researchers developed a transgenic variety, the "MitoFish," that enables them to see -- within individual neurons of living animals -- how brain diseases disturb the transport of mitochondria, the power plants of the cell.