Vertex Pharmaceuticals Incorporated Announces Webcast Of Its Presentation At The MASS Opportunities Biotechnology Investment Conference 2005

CAMBRIDGE, Mass., Oct. 31 /PRNewswire-FirstCall/ -- Vertex Pharmaceuticals Incorporated will webcast its corporate presentation at the MASS Opportunities Biotechnology Investment Conference 2005. The MASS Opportunities Conference is hosted by the Massachusetts Biotechnology Council (MBC). The presentation will be delivered by Lynne Brum, Vertex's Vice President of Corporate Communications and Financial Planning on Thursday, November 3, 2005 at 11:40 a.m. EST.

The presentation will be webcast live and may be accessed by visiting the Vertex website at http://www.vrtx.com. A replay of the webcast will also be available on the Company's website until November 14, 2005. To access the webcast, go to Vertex's website and select the 'MASS Opportunities: A Biotechnology Investment Conference' from the 'Events Calendar.' To ensure a timely connection to the webcast, it is recommended that users register at least 15 minutes prior to the scheduled webcast.

About Vertex

Vertex Pharmaceuticals Incorporated is a global biotechnology company committed to the discovery and development of breakthrough small molecule drugs for serious diseases. The Company's strategy is to commercialize its products both independently and in collaboration with major pharmaceutical companies. Vertex's product pipeline is principally focused on viral diseases, inflammation, autoimmune diseases and cancer. Vertex co-promotes the HIV protease inhibitor, Lexiva, with GlaxoSmithKline.

Lexiva is a registered trademark of the GlaxoSmithKline group of companies.

Vertex's press releases are available at http://www.vrtx.com. Vertex Contact: Lora Pike, Manager, Investor Relations, (617) 444-6755

Vertex Pharmaceuticals Incorporated

CONTACT: Lora Pike, Manager, Investor Relations of Vertex PharmaceuticalsIncorporated, +1-617-444-6755

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