To-BBB technologies BV And GlaxoSmithKline To Collaborate On Brain Delivery Of A Biologic Product

Published: Mar 03, 2010

Leiden, 03 March 2010 to-BBB, the Dutch brain drug delivery company announced today that it has entered into a research collaboration with GlaxoSmithKline (GSK) involving to-BBB’s proprietary G-Technology® in delivering a biological compound to the brain.

Under the terms of the collaboration, to-BBB will work with scientists at the GSK R&D centre in Shanghai, China to further evaluate the brain delivery of treatments enhanced with to-BBB’s G-Technology.

G-Technology is designed to enhance transport of medicines across the blood-brain barrier by encapsulating these compounds into proprietary glutathione coated liposomes. The company has shown proof of concept in different disease models and GSK will now assess the technology with GSK nominated compounds.

“We look forward to working with the scientists at GSK R&D China.” says Pieter Gaillard, CSO of to-BBB. “Combining the expertise of GSK in the area of neurobiology with to-BBB’s brain targeting knowledge, we hope will lead to advances in the treatment of diseases that affect the brain.”

About to-BBB

to-BBB is a Dutch biotechnology company in the field of enhanced drug delivery across the blood-brain barrier. The company is developing novel treatments for brain disorders by combining existing drugs with its proprietary brain drug delivery platform. The company’s vision is that the treatment of currently unserved brain diseases will be best achieved by safely enhancing the blood-to-brain delivery of drugs.

to-BBB is headquartered in The Netherlands at the Leiden Bio Science Park and has established a fully owned subsidiary, to-BBB Taiwan Ltd., in Taipei, Taiwan.

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