Thermo Fisher Scientific Enhances Glycan Analysis Workflow With Simultaneous Charge, Size and Polarity HPLC Separations
Published: Feb 04, 2013
SAN JOSE, Calif.--(BUSINESS WIRE)--Thermo Fisher Scientific Inc., the world leader in serving science, today introduced the Thermo Scientific Dionex GlycanPac AXH-1 HPLC column. This new column is designed to enable simultaneous separation of biologically-important glycans based on charge, size and polarity, and facilitate challenging characterization of glycan profiles and determination of their structures. Growing numbers of scientists are investigating glycans as potential biomarkers or as post-translational modifications of therapeutic proteins, as evidenced by large numbers of published studies. Antibody research is gaining growing interest in developing protein biotherapeutics, including monoclonal antibodies for the treatment of diseases. Glycosylation of antibodies is a major source of structural and functional variation and can profoundly affect the safety and effectiveness of biopharmaceutical products.