Sirona Biochem Reaches Major Milestone By Successful Scale-Up Of Skin Lightening Compound SBM-TFC-1067

Formulation testing by potential licensee gets underway shortly

Vancouver, British Columbia – September 15, 2015 – Sirona Biochem Corp. (TSX-V: SBM, Frankfurt: ZSB, Xetra®: ZSB.DE) (the "Company") is pleased to announce the successful scale-up of its skin lightening compound SBM-TFC-1067 ("1067").

Sirona Biochem commissioned its contract research organization (CRO) Roowin ( for the scale-up of 1 kg of 1067 compound. The successful scale-up represents a major scientific breakthrough by Sirona’s laboratory in Rouen, France. A quantity of 200 grams of 1067 was delivered last week for formulation and solubility testing by a major multinational corporation under a previously signed material transfer agreement.

One of the major differentiators between 1067 and Sirona’s earlier generation skin lightening compounds is that the chemical process of applying Sirona's proprietary fluorination technology now requires only three steps to yield a final product. This results in a highly favourable cost of goods (COGs) and more importantly, a product with very profitable commercial viability. A preliminary estimation of COGs for the active ingredient yielded $0.10 CAD per 100 ml final formulation at a final concentration of 0.1%.

Dr. Howard Verrico, CEO of Sirona Biochem, states, “Formulation testing on this quantity of compound represents a major milestone in the development of 1067, which will ultimately result in a successful licensing deal with one of the top cosmetic companies in the world.” He further stated, “This is the first time in Sirona’s history that we have advanced a cosmetic compound to formulation testing.”

Attila Hajdu, Chief Business Development Officer at Sirona Biochem, said, “Potential partners have replicated in vitro tests that we have done in the past to double-check our efficacy and safety data, and whatever else meets their needs to justify further collaboration. The request for formulation testing was a pleasant surprise for us because we originally anticipated that formulation work would occur after a licensing deal. This is a very exciting development.”

For more information regarding this press release, please contact:
Christopher Hopton, CFO
Sirona Biochem Corp.
Phone: 1.604.282.6064

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