Sequenta, Inc. Develops Novel Method for Identifying Antigen-Specific T Cells by Combining Conventional Immune Monitoring Assays With High-Throughput Repertoire Sequencing

Published: Sep 20, 2013

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SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Sequenta, Inc., today published results demonstrating that a combination of traditional immune assays and next-generation sequencing can be used to characterize immune responses at a level not possible using standard assays alone. Conventional immune monitoring assays, which enable identification of populations of T cells that either bind to or respond to antigen via T cell receptors, are able to provide information on only the totality of an immune response. These assays alone cannot be used to characterize the component T cells (called “clonotypes”) that together contribute to an immune response.

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