ReNeuron To Present Key Safety Data At Leading European Molecular Biology Scientific Conference
A poster presentation at the conference will describe key safety characteristics regarding ReNeuron’s c-mycER stem cell expansion technology. This technology has been used to efficiently scale up the Company’s lead CTX stem cell line, the first application for which is the Company’s ReN001 therapy for stroke.
ReNeuron’s c-mycER cell expansion technology is fully controllable by means of a chemical safety switch, so that it becomes inactive prior to implantation of the expanded cells. The conference poster describes a study in a pre-clinical model of stroke, demonstrating a further safety feature of the expansion technology. In the study, expression of the c-mycER transgene is shown to be silenced in vivo, thereby nullifying any impact of the expansion technology after implantation of the lead CTX stem cell line.
Initial data from this study have been included in the pre-clinical safety data package submitted to regulators in support of the Company’s applications to commence initial clinical trials with ReN001.
More information about the conference may be found at www-db.embl.de/jss/EmblGroupsOrg/conf_82. About ReNeuron
ReNeuron is a leading, UK-based stem cell company. Its primary objective is the development of stem cell therapies targeting areas of significant unmet or poorly met medical need.
ReNeuron has filed for approval to commence initial clinical studies with its lead ReN001 stem cell therapy for disabled stroke patients in both the USA and the UK. There are an estimated 50 million stroke survivors worldwide, approximately one half of which are left with permanent disabilities. The annual health and social costs of caring for these patients is estimated to be in excess of £5 billion in the UK and in excess of US$50 billion in the USA. In addition to its stroke programme, ReNeuron is developing stem cell therapies for a number of other conditions, including peripheral ischaemia, Type 1 diabetes and diseases of the retina.
ReNeuron has also developed a range of stem cell lines for non-therapeutic applications – its ReNcell® products for use in academic and commercial research. The Company’s ReNcell®CX and ReNcell®VM neural cell lines are marketed worldwide under license by USA-based Millipore Corporation.
ReNeuron’s shares are traded on the London AIM market under the symbol RENE.L. Further information on ReNeuron and its products can be found at www.reneuron.com.
Data sources: UK Stroke Association; American Stroke Association
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