PreludeDx Presents Promising Research in Stage 1 Breast Cancer Patients at the 2018 San Antonio Breast Cancer Symposium
LAGUNA HILLS, Calif., /PRNewswire/ -- Prelude Corporation (PreludeDx), a leader in molecular diagnostics and personalized medicine for early stage breast cancer, announced today its compelling data from research on stage 1 breast cancer patients presented at the 2018 San Antonio Breast Cancer Symposium in San Antonio, TX. The data shows that PreludeDx's newly-developed assay can stratify risk of local recurrence in stage 1 breast cancer patients.
The study data shared by Dr. Troy Bremer, Chief Scientific Officer of PreludeDx, demonstrated that the new test was able to stratify patients where those in the low risk group had a 6% local 10-yr invasive recurrence risk with surgery alone or surgery and radiation therapy. Patients in the elevated risk group had a 49% risk of local invasive recurrence when treated with surgery alone but had a substantial benefit from radiation therapy.
As outcomes for early stage breast cancer patients improve, the oncology community has asked for more specific data on local control as they move from looking at distant metastases to local recurrence risk. One surprising finding was that elevated risk patients with surgery alone had nearly a 50% chance of developing invasive breast cancer in 10 years and still had a substantial recurrence risk of 31% with adjuvant radiation therapy. "This research represents a first step toward incorporating biomarker findings to inform local-regional management," said Pat Whitworth, MD, Director of Nashville Breast Center and Chief Science Officer of TME Breast Care Network. "This new test from PreludeDx promises to add 10-year local control information to 10-year distant metastasis-free survival when doctors consider tumor biology and management for an individual patient."
Daniel Forche, PreludeDx President and CEO stated "Our mission at PreludeDx is to improve the lives of early stage breast cancer patients. Following the success of DCISionRT for DCIS patients, we are very pleased with these research efforts to develop a new assay that can provide additional refinement of treatment for stage 1 breast cancer patients. These results will be expanded to the full data set that includes over 500 patients. We look forward to sharing the complete results at one of the premier oncology symposia in 2019 with additional clinical validations to follow."
About DCISionRT for Breast DCIS
For more information on how PreludeDx is making a difference for patients, please visit the Company's website: www.preludedx.com and follow us on Twitter @PreludeDx, Facebook and LinkedIn.
PreludeDx, the PreludeDx logo, DCISionRT, the DCISionRT logo, Decision Score, The DCIS Test, Know Your Risk, Know Her Risk, and Your Biology, Your Decision are trademarks of Prelude Corporation or its wholly owned subsidiaries in the United States and foreign countries.
View original content to download multimedia:http://www.prnewswire.com/news-releases/preludedx-presents-promising-research-in-stage-1-breast-cancer-patients-at-the-2018-san-antonio-breast-cancer-symposium-300761504.html