New Drug-eluting Contact Lens to Provide Timed Drug Delivery Directly to Eye; Improving Recovery, Reducing Cost for Millions after Eye Surgery and LASIK
The new, extended-wear contact, developed by Biomedical researchers at Rowan University and Auburn University, controls the release of anti-inflammatory, anti-biotic and pain reducing drugs that are delivered evenly over time. The new technology can potentially reduce recovery time and post-operative complications thereby reducing health care cost.
“Patients who undergo eye surgery for cataracts, LASIK or who suffer corneal abrasions can experience longer healing times, complications, and even infections if proper care, including administering eye drops, is not properly followed,” said Mark E. Byrne, PhD, Founding Head and Professor of Biomedical Engineering at Rowan University, inventor of the technology, and previously a distinguished professor at Auburn University and Chief Technical Officer of OcuMedic, Inc. “Our research shows the new contact lens technology is expected to lead to higher efficacy for patients compared to topical eye drops by improving compliance and mitigating concentration peaks and valleys associated with multiple drops.”
“In addition to serving patients who have undergone surgery, as a platform technology, the therapeutic lens has been applied to other diseases of the eye including Dry Eye and Glaucoma,” said Keith D. Ignotz, President and Chief Executive Officer of OcuMedic, Inc. which is commercializing the technology. “The current therapeutic eye drops market is $16 billion annually. A successful drug-eluting, soft contact lens - that could potentially capture a large part of that market - is expected to garner significant interest from large pharma companies.”
OcuMedic is expected to begin clinical studies necessary for U.S. Food and Drug Administration (FDA) approval this year, first as an in-vivo study for the FDA to navigate into the Phase 1 – 2 human trials in 2019.
The technology is covered by nine U.S. patents and is expected to be the first product of its kind on the market, once approved.
Approximately six million Americans undergo some type of eye surgery every year – four million cataract and one million post-corneal abrasion surgeries and 800,000 Lasik procedures. All patients require post-operative care which includes eye drops which can wash out quickly with only about 5% of the therapy reaching the target tissue. Eye drops can be hard to administer, and the low delivered concentration of medication tends to aggravate post-operative complications costing $70 billion per year. Dry eye disease affects greater than five million people in the U.S. and approximately 40 million worldwide and is the most frequent complaint and reason to visit an eye care professional in the U.S. Approximately three million Americans suffer from Glaucoma, worldwide more than 60 million people are affected.
Dr. Byrne and OcuMedic have received approximately $1.85 million in funding to date, including research funding from the National Institutes of Health and has recently received an undisclosed amount from a national Angel investor group and is staging for a Series A funding in the $4 million range.
About OcuMedic, Inc.
OcuMedic, Inc. is the developer of the world’s first, drug-eluting therapeutic lens/clear corneal bandage for the delivery of drugs for the global ophthalmic market. Invented by Mark Byrne, Ph.D. distinguished engineering professor and Head of the Department of Biomedical Engineering at Rowan University, the therapeutics lens is a soft contact developed in the most widely used lens material that precisely controls the release of drugs that target post-operative eye care to reduce healing time and complications. The device is a platform technology, with OcuMedic demonstrating controlled release of a number of therapeutics for the duration of wear, targeted at the large and growing surgery, dry eye and glaucoma markets. For more information, visit http://ocumedic.net/.
(Editors please note: High-resolution images at http://ocumedic.net/techinspects/)
Bill Wells, 404-281-7490
Keith Ignotz, 404-444-6030
Source: OcuMedic, Inc.