Metabolomics Study Reveals 3-Indoxyl Sulfate as a Sensitive and Early Biomarker of Nephrotoxicity Report Investigators from Metabolon and Merck & Co., Inc.

RESEARCH TRIANGLE PARK, N.C.--(BUSINESS WIRE)--Metabolon, Inc., the leader in metabolomics, biomarker discovery and analysis, announces the publication of ”Metabolomics Analysis Reveals Elevation of 3-Indoxyl Sulfate in Plasma and Brain during Chemically-induced Acute Kidney Injury in Mice: Investigation of Nicotinic Acid Receptor Agonists”, in Toxicology and Applied Pharmacology (doi: 10.1016/j.taap.2011.05.015). The study was authored by Dr. Joanna R. Zgoda-Pols and colleagues at Merck Research Laboratories in New Jersey and scientists at Metabolon.