Lonza Walkersville, Inc. and Hyglos GmbH Reach Agreement for Endotoxin Detection Patents

Published: Mar 14, 2013

Walkersville, MD (USA) and Munich, Germany, March 14, 2013 / B3C newswire / – Lonza Walkersville, Inc. and Hyglos GmbH, a German biotech company, announced today that they have reached a mutually beneficial global settlement which includes a license agreement for Hyglos under certain Lonza patents in the area of endotoxin detection. Specifically, the agreement allows Hyglos to use recombinant factor C technology protected by Lonza’s patents to produce Hyglos’ own endotoxin products. The agreement also includes the dismissal of the law suit Lonza previously filed against Hyglos.

The terms of the settlement are confidential.

“Thanks to this agreement an important door has opened for a new era in endotoxin detection. We are convinced that Hyglos’ innovative assays, entirely based on recombinant molecules, are addressing important needs of endotoxin testing laboratories worldwide” said Dr. Wolfgang Mutter, General Manager of Hyglos GmbH.

“We are very glad to have reached this agreement with Hyglos. Endotoxin detection using recombinant factor C instead of Limulus amoebocyte lysates has recently been acknowledged by the FDA as an alternative method. We believe that this sustainable animal-free alternative will be the future of endotoxin detection.” concluded Dr. Teun Van der Heide, Head Lonza Bioscience.

About Hyglos

Hyglos is an internationally active biotech company based in Germany. Hyglos core competency is to exploit its proprietary phage-protein technology in developing recombinant proteins and enzymes applied in new and improved testing solutions. The Hyglos test kits are used in research, biopharmaceutical development and quality control as well as food and clinical microbiology. To this end Hyglos also collaborates with several world-leading companies. With the 2011 introduction of EndoLISA® - the world’s first solid-phase based method for endotoxin detection - Hyglos initiated its contribution to the important evolution of non-animal endotoxin testing. In January 2013, Hyglos extended its endotoxin detection portfolio with the commercial launch of EndoZyme® Recombinant Factor C (rFC) Assay. Further information can be found at www.hyglos.de.

About Lonza

Lonza is one of the world's leading suppliers to the pharmaceutical, healthcare and life science industries. Products and services span its customers’ needs from research to final product manufacture. It is the global leader in the production and support of chemical and biological active pharmaceutical ingredients. Biopharmaceuticals are one of the key growth drivers of the pharmaceutical and biotechnology industries. Lonza has strong capabilities in large and small molecules, peptides, amino acids and niche bioproducts which play an important role in the development of novel medicines and healthcare products. Lonza is also the world leader in microbial control providing innovative, chemistry-based and related solutions to destroy or to selectively inhibit the growth of harmful microorganisms. Its activities encompass the areas of water treatment, personal care, health and hygiene, industrial preservation, materials protection, and wood treatment. In addition, Lonza is a leader in cell-based research, endotoxin detection and cell therapy manufacturing. Furthermore, the company is a leading provider of value chemical and biotech ingredients to the nutrition and agro markets.

Lonza is headquartered in Basel, Switzerland and is listed on the SIX Swiss Exchange and secondary listed on the Singapore Exchange Securities Trading Limited (“SGX-ST”). Lonza is not subject to the SGX-ST’s continuing listing requirements. Lonza is subject to the listing rules of the SIX Swiss Exchange, which do not have specific requirements equivalent to the listing rules of the SGX-ST in respect of interested person transactions, acquisition and realizations, and delisting. In 2012, the company had sales of CHF 3.925 billion. Further information can be found at www.lonza.com.

Further Information

Lonza Group Ltd

Head of Corporate Communications

Dominik Werner

Tel +41 61 316 8798

Fax +41 61 316 9798


Lonza Group Ltd

Investor Relations

Dirk Oehlers

Tel +41 61 316 8540

Fax +41 61 316 9540


Lonza Group Ltd

Media Relations

Melanie Disa

Tel +1 201 316 9413

Fax +1 201 696 3533


Hyglos GmbH

Director Marketing & Sales

Karolina Heed

Tel +49 8158 9060 204

Fax +49 8158 9060 210


Hyglos GmbH

General Manager

Dr. Wolfgang Mutter

Tel +49 8158 9060 201

Fax +49 8158 9060 210


Back to news