Lankenau Institute for Medical Research Obtains Three New Grants To Further Research Cancer And Lupus Treatments

Published: Nov 13, 2015

(Wynnewood, PA, November 13, 2015) – The Lankenau Institute for Medical Research (LIMR), part of Main Line Health, has been awarded three grants to support ongoing clinical research. The National Institutes of Health (NIH) awarded two grants totaling $3.85M and the Lupus Research Institute (LRI) granted LIMR $300,000.

“We are extremely excited about the research opportunities that are now possible with the support of the NIH and LRI,” states George Prendergast, Ph.D., President and CEO of LIMR. “Our ongoing pancreatic and skin cancer research as well as developing lupus treatments will be greatly supported through these grants.”

The first grant from NIH, of $1.97 million, is to investigate the IDO pathway as a possible treatment target in pancreatic cancer. This targeted therapy for pancreatic cancer under, the direction of Dr. George Prendergast and Dr. Alexander Muller, Associate Professor at LIMR, is reportedly showing encouraging early results. The second NIH grant, of $1.88 million, is to study polyamine-stimulated stem cell recruitment in arsenic-induced skin cancer, under the direction of Susan K. Gilmour, Ph.D., Professor at LIMR.

In addition, the Lupus Research Institute granted LIMR $300,000, based on preliminary data generated by Dr. Laura Mandik-Nayak, associate professor at LIMR, securing a Lankenau Women’s Board award. Dr. Mandik-Nayak’s grant could lead to a new approach for the prevention and treatment of lupus and its related symptoms.


About Main Line Health

Founded in 1985, Main Line Health (MLH) is a not-for-profit health system serving portions of Philadelphia and its western suburbs. At its core are four of the region’s respected acute care hospitals—Lankenau Medical Center, Bryn Mawr Hospital, Paoli Hospital and Riddle Hospital—as well as one of the nation’s premier facilities for rehabilitative medicine, Bryn Mawr Rehab Hospital; Mirmont Treatment Center for drug and alcohol recovery; and HomeCare & Hospice, a home health service. Main Line Health also consists of Main Line HealthCare, one of the region’s largest multi-specialty physician networks, and the Lankenau Institute for Medical Research, a non-profit biomedical research organization located on the campus of Lankenau Medical Center. Main Line Health is also comprised of four outpatient health centers located in Broomall, Collegeville, Exton and Newtown Square. Main Line Health Hospitals, with more than 10,000 employees and 2,000 physicians, are the recipients of numerous awards for quality care and service, including System Magnet® designation, the nation’s highest distinction for nursing excellence. Main Line Health is among the area’s leaders in medicine, providing advanced patient-centered care, education and research to help our community stay healthy.

About Lankenau Institute for Medical Research

Founded in 1927, the Lankenau Institute for Medical Research (LIMR) is an independent, nonprofit biomedical research center located in suburban Philadelphia on the campus of Lankenau Medical Center. Part of Main Line Health, LIMR is one of the few freestanding, hospital associated medical research centers in the nation. The faculty and staff at the Institute are dedicated to advancing an understanding of the causes of cancer, heart disease and diabetes. This information is used to help improve diagnosis and treatment of these diseases as well as find ways to prevent them. LIMR is also committed to extending the boundaries of human health and well-being through technology development and the training of the next generation of scientists and physicians. To learn about LIMR, visit

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