FORMA Therapeutics and the University of Oxford Announce Multi-Year Collaboration to Advance the Development of Deubiquitinating Enzyme (DUB) Inhibitors for the Treatment of Neurodegenerative Diseases
FORMA Therapeutics' scientists are passionate about discovering and developing medicines that will make a difference in oncology, inflammation & immunity, neurodegeneration, and other serious diseases. The Company’s fully integrated R&D team drives discovery and early clinical development of therapeutics for qualified targets in the areas of epigenetics, protein homeostasis and metabolism. Leveraging a world class network of academic investigators, clinical experts and partners, FORMA combines deep biology insight, chemistry expertise and early clinical development capabilities, to create drug candidates providing profound patient benefit.
FORMA is headquartered in Watertown, MA near the epicenter of the Cambridge Life Sciences cluster, with operations in Watertown, MA and Branford, CT. www.formatherapeutics.com
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About the ARUK Oxford Drug Discovery Institute and the Oxford Parkinson’s Disease Centre
The Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) is a drug discovery team, founded with funding from the charity Alzheimer’s Research UK, with the objective of accelerating the translation of basic science generated within universities towards therapeutic utility. The focus of the team is upon discovering treatments for the neurodegenerative diseases underlying the dementias. Although Alzheimer’s disease is the most common cause of dementia and the charity bears its name, the remit of the ODDI covers all diseases and mechanisms implicated in the different neurodegenerative diseases that contribute to dementia, including Alzheimer’s disease, Parkinson’s disease, vascular dementia and frontotemporal dementia. The Oxford Parkinson’s Disease Centre (OPDC; www.opdc.ox.ac.uk) is an international research Centre for Parkinson's disease established in February 2010. It brings together internationally-recognised scientists with strengths in stem cell models, genetics and genomics, transgenic rodent models, the structure and function of brain cells and circuits affected in PD, magnetic resonance imaging (MRI), and analysis of protein biomarkers. Working closely with experts in epidemiology and clinical neurology the program is now focused on using the experimental platforms developed to identify and validate new disease modifying approaches and also match these to the patient groups most likely to benefit from them.
Source: FORMA Therapeutics