Cryoprinting Red Blood Cells: Akron Biotechnology, LLC And Stanford University Collaborative Study

Published: Aug 11, 2014

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BOCA RATON, Fla.--(BUSINESS WIRE)--An innovative approach of cryopreserving red blood cells using vitrification in conjunction with bio-printing technologies has been described in a new collaborative study published this week in Advanced Materials. The study, led by Dr. Utkan Demirci, is a collaboration involving scientists from Stanford University School of Medicine, Harvard Medical School, Case Western Reserve University, Worcester Polytechnic Institute, and Akron Biotechnology.

Titled “Bio-Inspired Cryo-Ink Preserves Red Blood Cell Phenotype and Function During Nanoliter Vitrification”, the study describes the use of a bio-printer which generates nanoliter droplets containing red blood cells (RBCs). The RBCs can then be rapidly vitrified using a bio-inspired cryoprotectant. The cryoprotectant in question is glycerol- and DMSO-free and based on ectoine, a naturally occurring organic compound, while the cryo-printer is composed of an ejector-based system which produces nanoliter-volume droplets.

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