Cell Signaling Technology, Inc. Granted Patent for PCR Methods for Detection of a Subset of Treatable Non-Small Cell Lung Cancers
Published: Jan 07, 2013
DANVERS, Mass.--(BUSINESS WIRE)--Cell Signaling Technology, Inc. (CST) of Danvers, MA, announced today the issuance of US Patent No. 8,288,102, relating to PCR-based methods for the detection of EML4-ALK (anaplastic lymphoma kinase) polynucleotides in patient samples. The presence of the fusion kinase EML4-ALK has been reported in a subset of patients with breast, colon, and non-small cell lung cancer (NSCLC). Pfizer’s XALKORI® (crizotinib) is approved in the US for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with ALK fusions as detected by an FDA-approved test.