Caliper Life Sciences, Inc. Reports Q1 2006 Financial Results

HOPKINTON, Mass., May 10 /PRNewswire-FirstCall/ -- Caliper Life Sciences, Inc. today reported financial results for the quarter ended March 31, 2006. Total revenues for the first quarter were $22.3 million, an increase of 21% from $18.4 million in the first quarter of 2005. Excluding unfavorable effects of foreign exchange rate movements, revenues increased from the prior year quarter by 24%, which includes 11% organic growth.

The company reported net loss on a GAAP basis of $4.4 million ($0.13 per share) in comparison with a GAAP net loss of $4.9 million ($0.16 per share) in the first quarter of 2005. Gross margins from product and services remained flat at 36% in the first quarter in comparison to the first quarter of 2005. Total operating expenses (R&D plus SG&A) were $12.9 million, up approximately 10% from $11.8 million in the same period of 2005. The company's cash and marketable securities as of March 31, 2006 totaled $26.8 million.

Commencing with this quarter, Caliper is initiating a practice of supplementing its GAAP financial reporting with certain non-GAAP financial measures. A reconciliation of Caliper's GAAP Statements of Operations to the non-GAAP Statements of Operations is provided at the end of this release under "Adjusted Consolidated Statements of Operations." Adjusted results of operations, discussed in the paragraph below, exclude stock-based compensation charges, including those related to Caliper's January 1, 2006 adoption of FAS 123R, and acquisition-related expenses, such as amortization of intangibles and restructuring charges and credits. Caliper believes that providing this additional financial information will enhance the reader's understanding of the financial performance of Caliper's operations and increase the comparability of its current financial statements to prior periods.

The first quarter 2006 adjusted net loss was $1.9 million ($0.06 per share) compared with $3.5 million ($0.12 per share) in the prior year. Adjusted gross margins from products and services for the first quarter of 2006 increased to 37% from 36% over the first quarter of 2005. Adjusted operating expenses were $11.8 million, up 3% from $11.4 million in the same period of 2005. This increase reflects the addition of expenses from NovaScreen Biosciences, which Caliper acquired in the fourth quarter of 2005, partially offset by spending reductions in other parts of Caliper's business.

Service revenues in the first quarter increased 55%, due primarily to the addition of NovaScreen revenues. Product revenues grew by 12%, driven by continued strength in Caliper's microfluidics business. The installed base of the company's LabChip 3000 Drug Discovery and LabChip 90 Electrophoresis Systems is now over 130 units. Other product milestones included the recent launch of Caliper's next-generation Tablet Processing Workstation (TPW3) and Active Ingredient Processing Workstation (APW3).

"Our first quarter organic growth rate of 11% has gotten us off to a solid start in 2006," said Kevin Hrusovsky, president and CEO at Caliper. "LabChip systems continued to sell at an accelerated pace during the first quarter, a trend we began to see in the third quarter of 2005 when unit sales jumped to roughly double historical rates. Microfluidics revenues grew over 40% from the first quarter of last year."

"We are also pleased to see the TPW3/APW3 launch on schedule after an intensive development program guided by several of our key customers. These new drug development workstations should benefit our revenue performance in the second half of the year. In the near term, we are projecting Q2 revenues of $22 to 24 million."

During the first quarter of 2006 Caliper announced its planned acquisition of Xenogen Corporation, a maker of advanced imaging systems including instruments, biological solutions and software designed to accelerate drug discovery and development. On May 9, 2006 Xenogen reported first quarter revenues of $8.7 million as compared to $9.3 million for the first quarter of 2005. Xenogen management acknowledged that its first quarter revenue was below their expectations, and attributed the first quarter revenue decline to record level revenue performance at the end of 2005 and to distractions related to the pending merger. Xenogen management also stated that April appears to be a strong start for the second quarter. Caliper is evaluating each of these conclusions and their impact.

Caliper will webcast its first quarter results conference call starting at 9:00 a.m. EDT today. To listen to the webcast, visit http://www.fulldisclosure.com or the investor relations section of Caliper's website at www.caliperLS.com. The webcast will be available for replay from May 10th until Caliper's earnings call for the second quarter of 2006.

A telephone replay is also available until May 17th by dialing 888-286-8010 and entering the passcode 68778591. International dialers can access the replay by dialing 617-801-6888 and using the same passcode.

About Caliper Life Sciences

Caliper Life Sciences is a leading provider of drug discovery and life sciences research solutions for the pharmaceutical and biotechnology industries. Caliper's mission is to transform drug discovery and diagnostics by offering a comprehensive array of products and services for clinically relevant experimentation. Based in Hopkinton, Massachusetts, Caliper services approximately 80 percent of the world's leading pharmaceutical companies through representation in thirty countries. More information about Caliper and its products and services can be found on the web at www.caliperLS.com.

The statements in this press release regarding Caliper's pending acquisition of Xenogen Corporation, as well as statements regarding Caliper's outlook for revenues for the second quarter of 2006, including the potential benefits of TPW3 and APW3 workstations to Caliper's revenue performance, are "forward-looking statements" within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended. These statements are subject to risks and uncertainties that could cause actual results to differ materially from those contemplated by the forward-looking statement as a result of a number of factors, including the risk that Caliper may not be able to close its expected acquisition of Xenogen Corporation for, among other reasons, an inability to obtain required stockholder approvals, and the risks that unexpected difficulties may be encountered in gaining wider adoption of Caliper's new products, and that Caliper's expectations regarding demand for its products and services may not materialize if capital spending by Caliper's customers declines, if competitors introduce new competitive products, or if Caliper is unable to convince potential customers regarding the superior performance of its drug discovery systems and other products. Further information on risks faced by Caliper are detailed under the caption "Factors Affecting Operating Results" in Caliper's Annual Report on Form 10-K filed with the Securities and Exchange Commission on March 14, 2006. This filing is available on a web site maintained by the Securities and Exchange Commission at http://www.sec.gov . Caliper does not undertake any obligation to update forward-looking or other statements in this release or the conference call.

NOTE: Caliper and LabChip are registered trademarks and TPW and APW are trademarks of Caliper Life Sciences, Inc.

Important Notice

On April 3, 2006 Caliper Life Sciences, Inc. filed a preliminary Registration Statement on Form S-4 in order to register the shares of its common stock and warrants to be issued to the former stockholders of Xenogen in the proposed merger described above. The Form S-4 included a joint proxy statement for Caliper Life Sciences, Inc. and Xenogen Corporation. Investors and security holders of Caliper Life Sciences, Inc. and Xenogen Corporation are advised to read the Registration Statement on Form S-4 and the joint proxy statement regarding the proposed merger referred to in this communication when they are declared effective by the Securities and Exchange Commission and become available because they will contain important information. Caliper Life Sciences, Inc. and Xenogen Corporation expect to mail the joint proxy statement about the proposed merger to their respective stockholders. Investors and security holders may obtain a free copy of the proxy statement and any other documents filed by Caliper Life Sciences, Inc. and Xenogen Corporation at the Securities and Exchange Commission's web site at http://www.sec.gov and directly from Caliper Life Sciences, Inc. and Xenogen Corporation, respectively.

Caliper Life Sciences, Inc. and its officers and directors may be deemed to be participants in the solicitation of proxies from stockholders of Caliper Life Sciences, Inc. with respect to the proposed merger. Information regarding such officers and directors is included in Caliper Life Sciences, Inc.'s Annual Report on Form 10-K for the fiscal year ended December 31, 2005 filed with the Securities and Exchange Commission. This document is available free of charge at the Securities and Exchange Commission's web site at http://www.sec.gov and directly from Caliper Life Sciences, Inc.

CALIPER LIFE SCIENCES, INC. SELECTED FINANCIAL INFORMATION (Unaudited) CONSOLIDATED STATEMENTS OF OPERATIONS Three Months Ended (in thousands except per share data) March 31, 2006 2005 Revenues: Product revenue $14,698 $13,138 Service revenue 5,043 3,256 License fees and contract revenue 2,558 2,008 Total revenues 22,299 18,402 Cost and Expenses: Cost of product revenue 9,789 8,831 Cost of service revenue 2,839 1,661 Research and development 4,458 4,019 Selling, general and administrative 8,476 7,769 Amortization of intangible assets 1,254 898 Restructuring charges 42 90 Total costs and expenses (1) 26,858 23,268 Loss from operations (4,559) (4,866) Interest income, net 191 232 Other income (expense), net 53 (212) Provision for income taxes (134) (84) Net loss $(4,449) $(4,930) Net loss per share - basic and diluted $(0.13) $(0.16) Shares used in computing net loss per share - basic and diluted 33,518 30,453 (1) Stock-based compensation expense included within costs and expenses: Cost of product revenue $127 $39 Cost of service revenue 25 7 Research and development 240 82 Selling, general and administrative 894 287 Total $1,286 $415 CALIPER LIFE SCIENCES, INC. SELECTED FINANCIAL INFORMATION CONSOLIDATED BALANCE SHEETS (in thousands) March 31, December 31 2006 2005 (Unaudited) (Note 1) Assets Current assets: Cash and cash equivalents $7,023 $8,096 Marketable securities 19,817 23,129 Restricted cash 667 479 Accounts receivable, net 17,341 19,532 Inventories 12,260 11,061 Other current assets 3,147 2,657 Total current assets 60,255 64,954 Property and equipment, net 11,739 12,019 Intangible assets, net 15,569 16,822 Goodwill 60,866 60,866 Other assets 4,799 3,548 Total assets $153,228 $158,209 Liabilities and stockholders' equity Current liabilities $29,423 $31,204 Long-term obligations 8,189 8,567 Stockholders' equity 115,616 118,438 Total liabilities and stockholders' equity $153,228 $158,209 Note (1) Derived from audited financial statements for the year ended December 31, 2005. CALIPER LIFE SCIENCES, INC. ADJUSTED CONSOLIDATED STATEMENTS OF OPERATIONS Three Months Ended March 31, 2006 Reported Stock-based Other Adjusted (1) Comp Adjustments Revenues: Product revenue $14,698 $-- $-- $14,698 Service revenue 5,043 -- -- 5,043 License fees and contract revenue 2,558 -- -- 2,558 Total revenues 22,299 -- -- 22,299 Cost and Expenses: Cost of product revenue (2) 9,789 (127) -- 9,662 Cost of service revenue (2) 2,839 (25) -- 2,814 Research and development (2) 4,458 (240) -- 4,218 Selling, general and administrative (2) 8,476 (894) -- 7,582 Amortization of intangible assets (3) 1,254 -- (1,254) -- Restructuring charges (3) 42 -- (42) -- Total costs and expenses 26,858 (1,286) (1,296) 24,276 Loss from operations (4,559) 1,286 1,296 (1,977) Interest income, net 191 -- -- 191 Other income (expense), net 53 -- -- 53 Provision for income taxes (134) -- -- (134) Net loss $(4,449) $1,286 $1,296 $(1,867) Net loss per share - basic and diluted $(0.13) $(0.06) Shares used in computing net loss per share - basic and diluted 33,518 33,518 Three Months Ended March 31, 2005 Reported Stock-based Other Adjusted (1) Comp Adjustments Revenues: Product revenue $13,138 $-- $-- $13,138 Service revenue 3,256 -- -- 3,256 License fees and contract revenue 2,008 -- -- 2,008 Total revenues 18,402 -- -- 18,402 Cost and Expenses: Cost of product revenue (2) 8,831 (39) -- 8,792 Cost of service revenue (2) 1,661 (7) -- 1,654 Research and development (2) 4,019 (82) -- 3,937 Selling, general and administrative (2) 7,769 (287) -- 7,482 Amortization of intangible assets (3) 898 -- (898) -- Restructuring charges (3) 90 -- (90) -- Total costs and expenses 23,268 (415) (988) 21,865 Loss from operations (4,866) 415 988 (3,463) Interest income, net 232 -- -- 232 Other income (expense), net (212) -- -- (212) Provision for income taxes (84) -- -- (84) Net loss $(4,930) $415 $988 $(3,527) Net loss per share - basic and diluted $(0.16) $(0.12) Shares used in computing net loss per share - basic and diluted 30,453 30,453

(1) To supplement the financial results presented on a GAAP basis, the company uses adjusted measures of gross profit margins, costs and expenses, net loss and net loss per share which are non-GAAP financial measures. Caliper's management uses these adjusted financial measures to gain an understanding of its comparative operating performance, and also in financial and operating decision-making because management believes they better reflect the underlying economics of Caliper's ongoing business. Comparisons of adjusted financial measures may be more meaningful because operating results presented under GAAP may include, from time to time, items that are not necessarily relevant to understand Caliper's business. Caliper's management believes that these adjusted financial measures provide useful information to investors and others in understanding and evaluating Caliper's current operating performance and future prospects. The adjusted financial measures have limitations, however, because they do not include all items of income and expense that impact Caliper's operations. Management compensates for these limitations by presenting the tabular reconciliation above. The adjusted measures exclude:

a) Expense associated with non-cash stock compensation. The Company believes that available valuation methodologies and assumptions may result in estimates that are misleading in the comparison of its financial results to previous periods or to its peers, and do not provide meaningful insight into the Company's ongoing operations. The Company adopted Statement of Financial Accounting Standards (SFAS) No. 123R on January 1, 2006, which requires non-cash stock compensation expense to be recorded when stock options and other stock-related awards vest. The Company is using the modified-prospective transition method in its adoption of SFAS No. 123R and, as such, is not required to restate prior year results for the impact of option expensing. b) Expense associated with the amortization of acquisition-related intangible assets. This exclusion allows comparisons of operating results that are consistent over time for both the Company's newly acquired and long-held business activities and with both acquisitive and non-acquisitive peers. c) Restructuring expense related reductions in force and costs to discontinue activities including idle capacity costs. The costs largely relate to restructuring activities associated with business combinations and are not indicative of the company's normal operating costs.

Non-GAAP net income/(loss) and other non-GAAP financial measures disclosed by the Company should not be considered in isolation or as a substitute for GAAP.

(2) Adjustments represents stock-based compensation expense.

(3) Adjustment represents amortization of intangible assets acquired and restructuring activities related to business combinations.

Caliper Life Sciences, Inc.

CONTACT: Thomas Higgins, Chief Financial Officer, +1-508-497-2809, orMichele Boudreau, Director, Corporate Communications, +1-650-279-2088, bothof Caliper Life Sciences, Inc.; or Stacey Holifield of SchwartzCommunications, +1-781-684-0770, or stacey.holifield@schwartz-pr.com, forCaliper Life Sciences

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