Bruker Daltonics Inc.’s Novel maXis ETD Sets Dramatic New Records for Intact Protein Characterization and Top-down Sequencing at ASMS
Published: May 24, 2010
SALT LAKE CITY--(BUSINESS WIRE)--At the 58th ASMS Conference, Bruker and several collaborating scientists will present a number of milestone achievements in the analysis of intact proteins, including the direct sequencing and characterization using Bruker’s new maXis ETD system. The high mass accuracy, resolving power and dynamic range which are essential to dissect complex patterns of product ions in protein fragmentation allowed, for the first time, performing ETD-based tandem mass spectrometry on biomolecular ions above 60 kDa routinely. These results represent a new record for the mass spectrometric sequencing of intact proteins and unequivocally demonstrate the dramatic advantages of maXis ETD technology in ETD-based top-down protein structural analysis.