BioSphere Medical, Inc. Voluntarily Recalls HepaSphere (TM) Microspheres To Correct Package Defect

ROCKLAND, Mass.--(BUSINESS WIRE)--March 13, 2006--BioSphere Medical, Inc. (NASDAQ: BSMD) announced today that it has instituted a voluntary recall of its HepaSphere(TM) Microspheres in Europe and Japan to correct a packaging defect that the Company identified while conducting aging studies routinely performed on all its product packaging. HepaSphere Microspheres began shipping in late 2005.

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